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Condensed Statements of Stockholders’ Equity (unaudited) - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Other Comprehensive Loss
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2021   24,452,999      
Beginning balance at Dec. 31, 2021 $ 73,503 $ 24 $ 497,522 $ (272) $ (423,771)
Increase (Decrease) in Stockholders' Equity          
Net loss (11,461)       (11,461)
Unrealized loss on available-for-sale debt securities (710)     (710)  
Issuance of common stock pursuant to stock option exercises (in shares)   38,635      
Issuance of common stock pursuant to stock option exercises 1   1    
Repurchase of common stock (in shares)   (14,454)      
Repurchase of common stock 0        
Change in early exercise liability 2   2    
Stock-based compensation 1,488   1,488    
Ending balance (in shares) at Mar. 31, 2022   24,477,180      
Ending balance at Mar. 31, 2022 62,823 $ 24 499,013 (982) (435,232)
Beginning balance (in shares) at Dec. 31, 2021   24,452,999      
Beginning balance at Dec. 31, 2021 73,503 $ 24 497,522 (272) (423,771)
Increase (Decrease) in Stockholders' Equity          
Net loss (24,151)        
Unrealized loss on available-for-sale debt securities (1,179)        
Ending balance (in shares) at Jun. 30, 2022   24,814,855      
Ending balance at Jun. 30, 2022 52,902 $ 25 502,250 (1,451) (447,922)
Beginning balance (in shares) at Mar. 31, 2022   24,477,180      
Beginning balance at Mar. 31, 2022 62,823 $ 24 499,013 (982) (435,232)
Increase (Decrease) in Stockholders' Equity          
Net loss (12,690)       (12,690)
Unrealized loss on available-for-sale debt securities (469)     (469)  
Issuance of common stock pursuant to stock option exercises (in shares)   74,435      
Issuance of common stock pursuant to stock option exercises 2   2    
Issuance of shares pursuant to employee stock purchase plan (in shares)   147,217      
Stock issued during period, value, employee stock purchase plan 679 $ 1 678    
Issuance of common stock upon vesting of restricted stock units (in shares)   121,656      
Shares withheld for taxes (in shares)   (5,633)      
Shares withheld for taxes (47)   (47)    
Repurchase of common stock 0        
Change in early exercise liability 1   (1)    
Stock-based compensation 2,603   2,603    
Ending balance (in shares) at Jun. 30, 2022   24,814,855      
Ending balance at Jun. 30, 2022 $ 52,902 $ 25 502,250 (1,451) (447,922)
Beginning balance (in shares) at Dec. 31, 2022 25,045,751 25,045,751      
Beginning balance at Dec. 31, 2022 $ 34,777 $ 25 506,713 (1,108) (470,853)
Increase (Decrease) in Stockholders' Equity          
Net loss (10,375)       (10,375)
Unrealized loss adjustment for short-term investment 1,108     1,108  
Issuance of common stock pursuant to stock option exercises (in shares)   17,608      
Issuance of common stock pursuant to stock option exercises 1   1    
Issuance of common stock upon vesting of restricted stock units (in shares)   325,747      
Issuance of common stock upon vesting of restricted stock units 0        
Shares withheld for taxes (in shares)   (35,562)      
Shares withheld for taxes (146)   (146)    
Repurchase of common stock (in shares)   (1,340)      
Repurchase of common stock 0        
Stock-based compensation 2,125   2,125    
Ending balance (in shares) at Mar. 31, 2023   25,352,204      
Ending balance at Mar. 31, 2023 $ 27,490 $ 25 508,693 0 (481,228)
Beginning balance (in shares) at Dec. 31, 2022 25,045,751 25,045,751      
Beginning balance at Dec. 31, 2022 $ 34,777 $ 25 506,713 (1,108) (470,853)
Increase (Decrease) in Stockholders' Equity          
Net loss (19,499)        
Unrealized loss on available-for-sale debt securities $ 0        
Issuance of common stock pursuant to stock option exercises (in shares) 181,742        
Ending balance (in shares) at Jun. 30, 2023 25,816,929 25,816,929      
Ending balance at Jun. 30, 2023 $ 21,226 $ 26 511,552 0 (490,352)
Beginning balance (in shares) at Mar. 31, 2023   25,352,204      
Beginning balance at Mar. 31, 2023 27,490 $ 25 508,693 0 (481,228)
Increase (Decrease) in Stockholders' Equity          
Net loss (9,124)       (9,124)
Unrealized loss on available-for-sale debt securities 0        
Issuance of common stock pursuant to stock option exercises 5        
Stock issued during period, value, employee stock purchase plan 240        
Issuance of common stock upon vesting of restricted stock units 0        
Shares withheld for taxes (41)        
Change in early exercise liability 1        
Stock-based compensation $ 2,655        
Ending balance (in shares) at Jun. 30, 2023 25,816,929 25,816,929      
Ending balance at Jun. 30, 2023 $ 21,226 $ 26 $ 511,552 $ 0 $ (490,352)