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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' (DEFICIT) EQUITY (USD $) In Thousands, except Share data | Total | Ester | Proseed Capital Holdings | Common Shares | Common Shares Ester | Common Shares Proseed Capital Holdings | Additional Paid-in Capital | Additional Paid-in Capital Ester | Additional Paid-in Capital Proseed Capital Holdings | Treasury Stock | Accumulated Deficit
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning Balance at Dec. 31, 2008 | $ 8,416 |  |  | $ 25,664 |  |  | $ 202,107 |  |  | $ (217) | $ (219,138)
Beginning Balance (in shares) at Dec. 31, 2008 |  |  |  | 27,046,724 |  |  |  |  |  |  |
Stock issued (in shares) |  |  |  | 66,400,000 |  |  |  |  |  |  |
Stock issued | 62,253 |  |  | 54,212 |  |  | 8,041 |  |  |  |
Fair value of October 2009 warrant derivative liability | (47,105) |  |  |  |  |  | (47,105) |  |  |  |
Shares issued in repayment of bridge loans (in shares) |  |  |  | 3,999,996 |  |  |  |  |  |  |
Fair value of October 2009 warrants reclassed from derivative liability to equity | 5,328 |  |  |  |  |  |  |  |  |  |
Shares issued in repayment of bridge loans | 3,600 |  |  | 3,266 |  |  | 334 |  |  |  |
Transfer of fair value of bridge loan and December 2007 warrants from liabilities to equity | 5,328 |  |  |  |  |  | 5,328 |  |  |  |
Stock based compensation | 2,859 |  |  |  |  |  | 2,859 |  |  |  |
Loss and comprehensive loss | (30,606) |  |  |  |  |  |  |  |  |  | (30,606)
Shares issued (in shares) |  |  |  |  | 1,315,789 | 39,473 |  |  |  |  |
Shares issued |  | 1,801 | 51 |  | 1,046 | 31 |  | 755 | 20 |  |
Ending Balance at Dec. 31, 2009 | 6,597 |  |  | 84,219 |  |  | 172,339 |  |  | (217) | (249,744)
Ending Balance (in shares) at Dec. 31, 2009 |  |  |  | 98,801,982 |  |  |  |  |  |  |
Exercise of warrants (in shares) |  |  |  | 6,344,136 |  |  |  |  |  |  |
Exercise of warrants | 8,904 |  |  | 4,906 |  |  | 3,998 |  |  |  |
Exercise of stock options (in shares) |  |  |  | 1,706,016 |  |  |  |  |  |  |
Exercise of stock options | 3,642 |  |  | 1,336 |  |  | 2,306 |  |  |  |
Tax benefits realized from stock-based compensation | 543 |  |  |  |  |  | 543 |  |  |  |
Fair value of October 2009 warrants reclassed from derivative liability to equity | 22,317 |  |  |  |  |  | 22,317 |  |  |  |
Share issuances for services (in shares) |  |  |  | 4,597 |  |  |  |  |  |  |
Share issuances for services | 12 |  |  | 4 |  |  | 8 |  |  |  |
Stock based compensation | 5,207 |  |  |  |  |  | 5,207 |  |  |  |
Loss and comprehensive loss | (249,589) |  |  |  |  |  |  |  |  |  | (249,589)
Ending Balance at Dec. 31, 2010 | (202,367) |  |  | 90,465 |  |  | 206,718 |  |  | (217) | (499,333)
Ending Balance (in shares) at Dec. 31, 2010 |  |  |  | 106,856,731 |  |  |  |  |  |  |
Exercise of warrants (in shares) | 12,888,369 |  |  | 12,888,369 |  |  |  |  |  |  |
Exercise of warrants | 18,702 |  |  | 10,289 |  |  | 8,413 |  |  |  |
Exercise of stock options (in shares) | 2,273,221 |  |  | 2,273,221 |  |  |  |  |  |  |
Exercise of stock options | 5,094 |  |  | 1,833 |  |  | 3,261 |  |  |  |
Stock issued (in shares) |  |  |  | 13,800,000 |  |  |  |  |  |  |
Stock issued | 98,654 |  |  | 10,723 |  |  | 87,931 |  |  |  |
Tax benefits realized from stock-based compensation | 4,199 |  |  |  |  |  | 4,199 |  |  |  |
Fair value of October 2009 warrants reclassed from derivative liability to equity | 129,517 |  |  |  |  |  | 129,517 |  |  |  |
Share issuances for services (in shares) |  |  |  | 14,221 |  |  |  |  |  |  |
Share issuances for services | 71 |  |  | 11 |  |  | 60 |  |  |  |
Stock based compensation | 9,294 |  |  |  |  |  | 9,294 |  |  |  |
Loss and comprehensive loss | (69,126) |  |  |  |  |  |  |  |  |  | (69,126)
Ending Balance at Dec. 31, 2011 | $ (5,962) |  |  | $ 113,321 |  |  | $ 449,393 |  |  | $ (217) | $ (568,459)
Ending Balance (in shares) at Dec. 31, 2011 |  |  |  | 135,832,542 |  |  |  |  |  |  |

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- Definition Value stock issued during the period as a result of the exercise of stock options. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.3-04) -URI http://asc.fasb.org/extlink&oid=6959260&loc=d3e187085-122770 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 505 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=6928386&loc=d3e21463-112644 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher AICPA -Name Accounting Principles Board Opinion (APB) -Number 12 -Paragraph 10 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.29-31) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 04 -Article 3 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 29, 30, 31 -Article 5 + Details
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