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Commitments and Contingencies - Additional Information (Detail)
In Millions, unless otherwise specified
 12 Months Ended 1 Months Ended
Dec. 31, 2009
USD ($)
Mar. 31, 2012
Amr One Hundred One
USD ($)
Contract
Mar. 31, 2012
Amr One Hundred One
Maximum
USD ($)
Mar. 31, 2012
Amr One Hundred One
Maximum
Initial Payment
USD ($)
Jul. 31, 2011
Chemport
USD ($)
Mar. 31, 2012
Chemport
USD ($)
Dec. 31, 2009
Elan
USD ($)
Mar. 31, 2012
Up On First Marketing Approval of AMR101
USD ($)
Mar. 31, 2012
Net sales up to GBP100 million ($155 million at March 31, 2012)
Laxdale Limited
Mar. 31, 2012
Net sales up to GBP100 million ($155 million at March 31, 2012)
Laxdale Limited
Maximum
USD ($)
Mar. 31, 2012
Net sales up to GBP100 million ($155 million at March 31, 2012)
Laxdale Limited
Maximum
GBP (£)
Mar. 31, 2012
Net sales between GBP100 million ($155 million at March 31, 2012) and GBP500 million ($773 million at March 31, 2012)
Laxdale Limited
Mar. 31, 2012
Net sales between GBP100 million ($155 million at March 31, 2012) and GBP500 million ($773 million at March 31, 2012)
Laxdale Limited
Maximum
USD ($)
Mar. 31, 2012
Net sales between GBP100 million ($155 million at March 31, 2012) and GBP500 million ($773 million at March 31, 2012)
Laxdale Limited
Maximum
GBP (£)
Mar. 31, 2012
Net sales between GBP100 million ($155 million at March 31, 2012) and GBP500 million ($773 million at March 31, 2012)
Laxdale Limited
Minimum
USD ($)
Mar. 31, 2012
Net sales between GBP100 million ($155 million at March 31, 2012) and GBP500 million ($773 million at March 31, 2012)
Laxdale Limited
Minimum
GBP (£)
Mar. 31, 2012
Net sales in excess of GBP500 million ($773 million at March 31, 2012)
Laxdale Limited
Mar. 31, 2012
Net sales in excess of GBP500 million ($773 million at March 31, 2012)
Laxdale Limited
Minimum
USD ($)
Mar. 31, 2012
Net sales in excess of GBP500 million ($773 million at March 31, 2012)
Laxdale Limited
Minimum
GBP (£)
Mar. 31, 2012
First Indication for AMR101
Laxdale Limited
Potential Marketing Approval 1
USD ($)
Mar. 31, 2012
First Indication for AMR101
Laxdale Limited
Potential Marketing Approval 1
GBP (£)
Mar. 31, 2012
First Indication for AMR101
Laxdale Limited
Potential Marketing Approval 2
USD ($)
Mar. 31, 2012
First Indication for AMR101
Laxdale Limited
Potential Marketing Approval 2
GBP (£)
Mar. 31, 2012
First Indication for AMR101
Laxdale Limited
Maximum
USD ($)
Mar. 31, 2012
First Indication for AMR101
Laxdale Limited
Maximum
GBP (£)
Mar. 31, 2012
Further Indication for AMR101
Laxdale Limited
Potential Marketing Approval 1
USD ($)
Mar. 31, 2012
Further Indication for AMR101
Laxdale Limited
Potential Marketing Approval 1
GBP (£)
Mar. 31, 2012
Further Indication for AMR101
Laxdale Limited
Potential Marketing Approval 2
USD ($)
Mar. 31, 2012
Further Indication for AMR101
Laxdale Limited
Potential Marketing Approval 2
GBP (£)
Mar. 31, 2012
Further Indication for AMR101
Laxdale Limited
Maximum
USD ($)
Mar. 31, 2012
Further Indication for AMR101
Laxdale Limited
Maximum
GBP (£)
Commitments and Contingencies Disclosure [Line Items]                                                              
One-time non-refundable payment due to the supplier               $ 0.5                                              
Maximum penalty if the company is not successful in obtaining NDA approval for AMR101 5.0                                                            
Number of signed agreements   2                                                          
Development fees committed     0.5                                                        
Raw material purchase commitment   1.1   5.0                                                      
Minority share equity investment commitment           3.3                                                  
Cash paid for cost method investment         1.7                                                    
Potential milestone payments             0.2                                                
Potential royalty payment as a percentage of net sales                 1.00%     0.50%         0.25%                            
Net sales for potential royalty payments                   160 100   799 500 160 100   799 500                        
Potential aggregate stock or cash payment                                       $ 12.0 £ 7.5 $ 12.0 £ 7.5 $ 24.0 £ 15.0 $ 8.0 £ 5.0 $ 8.0 £ 5.0 $ 16.0 £ 10.0