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Difference between Benefit from Income Taxes and Amount Computed by Applying Statutory Income Tax Rate to Income Before Taxes (Detail) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Income Taxes [Line Items]      
Benefits from taxes at statutory rate $ (42,517) $ (16,652) $ (62,523)
Rate differential 13,249 3,952 3,871
Research credits     (1,014)
Change in valuation reserves 22,515 7,120 6,035
Permanent & other 6,809 2,209 17
Warrant derivative liabilities 8,904 5,643 52,761
Other 156 244 352
(Provision for) benefit from income taxes $ 9,116 $ 2,516 $ (501)