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Condensed Consolidated Statements of Operations (USD $)
In Thousands, except Share data, unless otherwise specified
 3 Months Ended 6 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Product revenues $ 5,500   $ 7,842  
Operating Expenses:        
Cost of goods sold 2,844   4,131  
Research and development 17,489 14,066 39,327 18,822
Selling, general and administrative 33,961 13,635 73,228 27,662
Total operating expenses 54,294 27,701 116,686 46,484
Operating loss (48,794) (27,701) (108,844) (46,484)
Gain (loss) on change in fair value of derivative liabilities 18,841 (18,930) 22,461 (85,139)
Interest expense, net (9,345) (4,317) (18,205) (8,268)
Other (expense) income, net (411) (52) (536) 16
Loss from operations before income taxes (39,709) (51,000) (105,124) (139,875)
(Provision for) benefit from income taxes (65) (2,904) 3,192 (2,314)
Net loss $ (39,774) $ (53,904) $ (101,932) $ (142,189)
Loss per share:        
Basic and diluted $ (0.26) $ (0.38) $ (0.68) $ (1.03)
Weighted average shares:        
Basic and diluted 150,694 140,550 150,562 138,280