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Significant Accounting Policies - Additional Information (Detail) (USD $)
 1 Months Ended 12 Months Ended
Oct. 31, 2009
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Significant Accounting Policies [Line Items]        
Sales discount percentage   2.00%    
Sales discount term   30 days    
Warrant derivative liability fair value assumptions, risk-free rate 2.37% 0.12% 0.25%  
Derivative liability fair value assumptions, term 5 years 9 months 18 days 1 year 9 months 18 days  
Warrant derivative liability fair value assumptions, dividend yield 0.00% 0.00% 0.00%  
Warrant derivative liability fair value assumptions, volatility rate 119.00% 99.00% 95.00%  
Gain (loss) on change in fair value of derivative liability   $ 47,710,000 $ (35,344,000) $ (22,669,000)
Market price of common stock   $ 1.97    
Hypothetical increase in market price of common shares   10.00%    
Long term debt redemption feature     14,600,000  
Effect of a hypothetical 10% increase in the market price of common shares
        
Significant Accounting Policies [Line Items]        
Increase (Decrease) in the fair value of warrant derivative liability   1,300,000    
Market price of common stock   $ 2.17    
Warrant
        
Significant Accounting Policies [Line Items]        
Warrant derivative liability 48,300,000 6,900,000 54,900,000  
Warrants Issued October 2009
        
Significant Accounting Policies [Line Items]        
Increase (Decrease) in the fair value of warrant derivative liability   (47,900,000) 35,600,000  
Gain (loss) on change in fair value of derivative liability   44,200,000 (35,400,000)  
Compensation expense (income) for change in fair value of warrants issued to former employees   (3,700,000) 200,000  
Embedded Derivative Financial Instruments
        
Significant Accounting Policies [Line Items]        
Gain (loss) on change in fair value of derivative liability   3,500,000 20,000  
Change of control obligation     140,000,000  
Maximum repayment of future revenue and receivables     150,000,000  
Long term debt redemption feature   11,100,000 14,600,000  
Foreign Exchange Forward
        
Significant Accounting Policies [Line Items]        
Net fair value, foreign exchange forward contracts   $ 0    
Top Three Customers | Gross Product Sales
        
Significant Accounting Policies [Line Items]        
Concentration risk percentage   96.00%    
Top Three Customers | Accounts Receivable
        
Significant Accounting Policies [Line Items]        
Concentration risk percentage   95.00%    
Largest Customer | Gross Product Sales
        
Significant Accounting Policies [Line Items]        
Concentration risk percentage   38.00%    
Largest Customer | Accounts Receivable
        
Significant Accounting Policies [Line Items]        
Concentration risk percentage   41.00%    
Maximum
        
Significant Accounting Policies [Line Items]        
Short term highly liquid instruments, maturity date   90 days    
Maximum | Embedded Derivative Financial Instruments
        
Significant Accounting Policies [Line Items]        
Derivative liability fair value assumptions, term   6 years 7 months 6 days 8 years  
Derivative liability fair value assumption, coupon rate   12.50% 11.50%  
Derivative liability fair value assumptions, market yields   29.40% 27.70%  
Minimum | Embedded Derivative Financial Instruments
        
Significant Accounting Policies [Line Items]        
Derivative liability fair value assumptions, term   3 years 3 months 18 days 4 years 9 months 18 days  
Derivative liability fair value assumption, coupon rate   9.90% 3.00%  
Derivative liability fair value assumptions, market yields   9.00% 10.70%