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Warrants and Warrant Derivative Liability - Additional Information (Detail) (USD $)
 1 Months Ended 1 Months Ended 12 Months Ended
Dec. 31, 2013
Oct. 31, 2009
October 2009 Private Placement
Dec. 31, 2013
October 2009 Private Placement
Warrants issued to three former officers
Oct. 16, 2009
October 2009 Private Placement
Warrants issued to three former officers
Oct. 31, 2009
October 2009 Private Placement
Bridge Loan
Oct. 16, 2009
October 2009 Private Placement
Bridge Loan
Dec. 31, 2013
October 2009 Private Placement
Warrants Issued October 2009
Oct. 16, 2009
October 2009 Private Placement
Warrants Issued October 2009
Oct. 16, 2009
October 2009 Private Placement
Warrants Issued October 2009
American Depositary Share
Dec. 31, 2013
October 2009 Private Placement
Warrants Issued October 2009
Maximum
Oct. 16, 2009
October 2009 Private Placement
Warrants Issued October 2009
Bridge Loan
American Depositary Share
Derivative [Line Items]                      
Number of warrant outstanding 9,789,776   600,000       7,500,000        
Exercise Price 1.44               1.50   1.50
Common stock issued under private placement, value   $ 70,000,000                  
Common stock issued under private placement, net proceeds   62,300,000                  
Bridge notes converted in conjunction with the private placement, amount         $ 3,600,000            
Common stock issued under private placement, shares   66,400,000     4,000,000            
Number of shares that each ADS represents   1     1            
Common stock issued under private placement, price per share   $ 1.00                  
Warrant term                 5 years   5 years
Warrants issued, number of shares called by the warrant                 0.5 36,100,000 0.5
Bridge notes converted in conjunction with the private placement, price per share           $ 0.90          
Number of warrants issued       900,000       35,200,000      
Description of pricing variability feature and classification of warrants             The warrants issued in connection with the October 2009 financing contained a pricing variability feature which provided for an increase to the exercise price if the exchange rate between the U.S. dollar and British pound adjusts such that the warrants could be exercised at a price less than the £0.5 par value of the common stock – that is, if the exchange rate exceeded U.S. $3.00 per £1.0 sterling. Due to the potential variable nature of the exercise price, the warrants are not considered to be indexed to the Company’s common stock. Accordingly, the warrants do not qualify for the exception to classify the warrants within equity and are classified as a derivative liability.