XML 45 R56.htm IDEA: XBRL DOCUMENT v2.4.0.8
Debt - Additional Information (Detail) (USD $)
 1 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended
Jan. 31, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Jan. 31, 2012
Convertible Debt
Dec. 31, 2013
Convertible Debt
Dec. 31, 2012
Convertible Debt
Dec. 31, 2013
Convertible Debt
Other current liabilities
Dec. 31, 2012
Convertible Debt
Other current liabilities
Dec. 31, 2013
Convertible Debt
American Depository Shares
Dec. 31, 2013
3.5% exchangeable senior notes due 2032
Finance
Dec. 31, 2012
3.5% exchangeable senior notes due 2032
Finance
Dec. 31, 2013
Proceeds
Convertible Debt
Dec. 31, 2013
Debt Offering
Convertible Debt
Dec. 31, 2012
Debt Offering
Convertible Debt
Dec. 31, 2012
Biopharma Debt
Sep. 30, 2013
Biopharma Debt
November 2013 for the fiscal quarter ended September 30, 2013
Dec. 31, 2012
Biopharma Debt
November 2013 for the fiscal quarter ended September 30, 2013
Dec. 31, 2012
Biopharma Debt
Per quarter in each of the next four quarters
Dec. 31, 2012
Biopharma Debt
Per quarter in each of the next four quarters
Dec. 31, 2012
Biopharma Debt
Per quarter in each of the next four quarters
Dec. 31, 2012
Biopharma Debt
Final payment
Dec. 31, 2013
Biopharma Debt
February 2014 for the fiscal quarter ended December 31, 2013
Dec. 31, 2013
Biopharma Debt
Cash
Dec. 31, 2012
Biopharma Debt
Cash
Dec. 31, 2013
Biopharma Debt
Non Cash
Dec. 31, 2012
Biopharma Debt
Non Cash
Debt Disclosure [Line Items]                                                      
Amount received at the closing of the agreement                               $ 100,000,000                      
Maximum repayment of future revenue and receivables                               150,000,000                      
Future minimum repayment under agreement                                 800,000 2,500,000 8,000,000 10,000,000 15,000,000 13,000,000 1,000,000        
Agreement expiration date                               Dec. 31, 2013                      
Change of control obligation                               140,000,000                      
Fair value of Embedded derivative liability     14,600,000                                                
Gain on change in fair value of derivative liability   3,500,000 20,000                                                
Interest expense   34,179,000 18,091,000 1,000                                       11,300,000 100,000 2,600,000 20,000
Convertible senior notes, principal amount         150,000,000                                            
Convertible senior notes, stated interest rate         3.50%                                            
Convertible senior notes, due date         2032                                            
Convertible senior notes, net proceeds     144,316,000   144,300,000                                            
Convertible senior notes, exchange rate of ADS per $1,000 principal amount of notes                   113.4752                                  
Convertible senior notes, total ADS into which the debt is exchangeable                   17,021,280                                  
Convertible senior notes, payment start date         Jul. 15, 2012                                            
Convertible senior notes, maturity date         Jan. 15, 2032                                            
Value of shares in excess of principal amount of Notes based on closing price     116,500,000                                                
Additional interest rate on notes per annum           0.50%                                          
Convertible senior notes, repurchase price at option of the issuer 100.00%                                                    
Proceeds allocated to conversion option     99,730,000     23,800,000                                          
Fair value of the liability component           126,200,000                                          
Note, estimated remaining life           24 months                                          
Effective interest rate           14.50%                                          
Unamortized debt discount           100,000 2,600,000           600,000                            
Debt discount amortization period           24 months                                          
Convertible notes, carrying amount net of unamortized discount           149,300,000 134,300,000                                        
Convertible notes, interest expense           20,300,000 18,000,000                                        
Interest expense, contractual coupon interest accrual           5,300,000 10,700,000                                        
Interest expense, amortization of discount           12,500,000 5,100,000             2,500,000 2,200,000                        
Accrued interest on convertible note   12,974,000 2,520,000         2,400,000 2,400,000                                    
Interest payment on notes   $ 6,090,000 $ 2,713,000               $ 5,300,000 $ 2,700,000