XML 24 R73.htm IDEA: XBRL DOCUMENT

Related Party Transaction - Additional Information (Detail) (USD $)					1 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011	Dec. 31, 2013 October 2009 Private Placement Warrant	Oct. 31, 2009 October 2009 Private Placement American Depository Share Point	Oct. 31, 2009 October 2009 Private Placement American Depository Share Abingworth LLP	Oct. 31, 2009 October 2009 Private Placement American Depository Share Orbimed Advisors LLC	Oct. 31, 2009 October 2009 Private Placement American Depository Share Sofinnova Venture Partners VII, LP	Oct. 31, 2009 October 2009 Private Placement American Depository Share Fountain Healthcare Partners Fund 1, LP
Related Party Transaction [Line Items]
Purchase of ADSs (in the form of common stock) by directors in private placement					$ 36,000,000	$ 17,000,000	$ 7,000,000	$ 7,000,000	$ 5,000,000
Number of ADS that can be purchased for each warrant received					0.5
Warrant derivative liability	17,994,000	69,431,000	123,125,000	6,900,000
Warrant derivative liability, fair value				$ 4,500,000

Fair value, after the effects of master netting arrangements, of a financial liability or contract with one or more underlyings, notional amount or payment provision or both, and the contract can be net settled by means outside the contract or delivery of an asset. Includes assets not subject to a master netting arrangement and not elected to be offset.

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