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Co-Promotion Agreement - Additional Information (Detail)
9 Months Ended
Sep. 30, 2014
Co-Promotion Agreement [Line Items]  
Promotion fee as a percentage gross margin From the high single digits in 2014, to mid-teen percent levels in 2015, and to the low twenty percent levels in 2018.
Kowa Pharmaceuticals America | Minimum
 
Co-Promotion Agreement [Line Items]  
Number of sales representatives 250