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Condensed Consolidated Statements of Operations (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2014
Sep. 30, 2013
Product revenues $ 14,149 $ 8,403 $ 37,722 $ 16,245
Less: Cost of goods sold 5,366 3,682 14,637 7,813
Gross margin 8,783 4,721 23,085 8,432
Operating expenses:        
Selling, general and administrative 19,270 28,274 60,949 101,502
Research and development 14,457 16,821 37,891 56,148
Total operating expenses 33,727 45,095 98,840 157,650
Operating loss (24,944) (40,374) (75,755) (149,218)
Gain (loss) on change in fair value of derivative liabilities 4,466 (1,402) 11,870 21,059
Gain on extinguishment of debt     38,034  
Interest expense, net (4,876) (8,441) (13,565) (26,646)
Other (expense) income, net (247) (302) 3,994 (838)
Loss from operations before taxes (25,601) (50,519) (35,422) (155,643)
(Provision for) benefit from income taxes (449) 1,635 (1,285) 4,827
Net loss $ (26,050) $ (48,884) $ (36,707) $ (150,816)
Loss per share:        
Basic $ (0.15) $ (0.29) $ (0.21) $ (0.96)
Diluted $ (0.17) $ (0.29) $ (0.25) $ (1.02)
Weighted average shares:        
Basic 174,502 170,187 173,426 157,105
Diluted 175,141 170,187 174,305 163,487