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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2014
Reconciliation of Total Amounts of Unrecognized Tax Benefits | The following is a reconciliation of the total amounts of unrecognized tax benefits for the years ended December 31, 2014, 2013 and 2012 (in thousands):
|  | 2014 |  |  | 2013 |  |  | 2012 |
Beginning uncertain tax benefits |  | $ | 1,674 |  |  | $ | 1,243 |  |  | $ | 997 |
Current year—increases |  |  | 1,067 |  |  |  | 687 |  |  |  | 294 |
Current year—decreases for lapses in statutes of limitations |  |  | (254 | ) |  |  | (256 | ) |  |  | (48 | )
Ending uncertain tax benefits |  | $ | 2,487 |  |  | $ | 1,674 |  |  | $ | 1,243 |
Jurisdictions the Company Remains Subject to Tax Examinations | The Company remains subject to tax examinations in the following jurisdictions as of December 31, 2014:
Jurisdiction |  | Tax Years |
United States (Federal and State) |  |  | 2011-2014 |
Ireland |  |  | 2009-2014 |
United Kingdom |  |  | 2013-2014 |
Components of Loss from Operations Before Taxes | The components of loss from operations before taxes were as follows at December 31, 2014, 2013 and 2012 (in thousands):
|  | 2014 |  |  | 2013 |  |  | 2012 |
United States |  | $ | (7,331 | ) |  | $ | (9,234 | ) |  | $ | 1,874 |
Ireland and United Kingdom |  |  | (51,870 | ) |  |  | (160,187 | ) |  |  | (171,942 | )
|  | $ | (59,201 | ) |  | $ | (169,421 | ) |  | $ | (170,068 | )
(Benefit) Expense from Income Taxes | The (benefit) expense from income taxes shown in the accompanying consolidated statements of operations consists of the following for fiscal 2014, 2013 and 2012 (in thousands):
|  | 2014 |  |  | 2013 |  |  | 2012 |
Current: |  |  |  |  |  |  |  |  |  |  |  |
Federal-U.S. |  | $ | 660 |  |  | $ | 122 |  |  | $ | 10,265 |
State-U.S. |  |  | 117 |  |  |  | 118 |  |  |  | 2,565 |
Total Current |  | $ | 777 |  |  | $ | 240 |  |  | $ | 12,830 |
Deferred: |  |  |  |  |  |  |  |  |  |  |  |
Federal-U.S. |  |  | (3,689 | ) |  |  | (4,065 | ) |  |  | (2,803 | )
State-U.S. |  |  | (226 | ) |  |  | 631 |  |  |  | (911 | )
Ireland and United Kingdom |  |  | 3,335 |  |  |  | (33,106 | ) |  |  | (22,515 | )
Change in valuation allowance |  |  | (3,034 | ) |  |  | 33,106 |  |  |  | 22,515 |
Total Deferred |  | $ | (3,614 | ) |  | $ | (3,434 | ) |  | $ | (3,714 | )
|  | $ | (2,837 | ) |  | $ | (3,194 | ) |  | $ | 9,116 |
Difference between (Benefit) Expense from Income Taxes and Amount Computed by Applying Statutory Income Tax Rate to Income Before Taxes | The (benefit) expense from income taxes differs from the amount computed by applying the statutory income tax rate to income before taxes due to the following for fiscal 2014, 2013 and 2012 (in thousands):
|  | 2014 |  |  | 2013 |  |  | 2012 |
Benefits from taxes at statutory rate |  | $ | (14,786 | ) |  | $ | (42,355 | ) |  | $ | (42,517 | )
Rate differential |  |  | 9,493 |  |  |  | 18,494 |  |  |  | 13,249 |
Change in valuation reserves |  |  | (3,034 | ) |  |  | 33,106 |  |  |  | 22,515 |
Warrant derivative liabilities |  |  | (2,706 | ) |  |  | (11,984 | ) |  |  | 8,904 |
Gain on extinguishment of debt |  |  | (9,509 | ) |  |  | — |  |  |  | — |
Research and development credits |  |  | (1,455 | ) |  |  | (2,008 | ) |  |  | (48 | )
Tax return to provision adjustments |  |  | 10,026 |  |  |  | 125 |  |  |  | 375 |
Cumulative translation adjustment |  |  | 8,061 |  |  |  | (280 | ) |  |  | — |
Permanent and other |  |  | 1,073 |  |  |  | 1,708 |  |  |  | 6,638 |
|  | $ | (2,837 | ) |  | $ | (3,194 | ) |  | $ | 9,116 |
Income Tax Effect of Each Type of Temporary Difference Comprising Net Deferred Tax Asset | The income tax effect of each type of temporary difference comprising the net deferred tax asset at December 31, 2014 and 2013 is as follows (in thousands):
|  | 2014 |  |  | 2013 |
Deferred tax assets: |  |  |  |  |  |  |  |
Net operating losses |  | $ | 80,096 |  |  | $ | 85,724 |
Stock based compensation |  |  | 15,600 |  |  |  | 11,660 |
Depreciation |  |  | (90 | ) |  |  | (126 | )
Tax credits |  |  | 2,141 |  |  |  | 1,256 |
Other reserves and accrued liabilities |  |  | 1,708 |  |  |  | 2,900 |
Gross deferred tax asset |  |  | 99,455 |  |  |  | 101,414 |
Less: valuation allowance |  |  | (85,965 | ) |  |  | (88,999 | )
|  | $ | 13,490 |  |  | $ | 12,415 |
Valuation Allowance | The following table reflects the activity in the valuation allowance for the years ended December 31, 2014 and 2013 (in thousands):
|  | 2014 |  |  | 2013 |
Beginning valuation allowance |  | $ | 88,999 |  |  | $ | 55,894 |
Increase as reflected in income tax expense |  |  | 5,081 |  |  |  | 32,999 |
Cumulative translation adjustment |  |  | (8,115 | ) |  |  | 106 |
Ending valuation allowance |  | $ | 85,965 |  |  | $ | 88,999 |

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