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Significant Accounting Policies - Additional Information (Detail)
 3 Months Ended 9 Months Ended
Sep. 30, 2015
USD ($)
Tranche
shares
Feb. 27, 2015
shares
Dec. 31, 2014
USD ($)
shares
Sep. 30, 2015
USD ($)
Tranche
shares
Sep. 30, 2014
USD ($)
Sep. 30, 2015
USD ($)
Tranche
Segment
shares
Sep. 30, 2014
USD ($)
Mar. 05, 2015
USD ($)
May. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Dec. 31, 2012
USD ($)
Significant Accounting Policies [Line Items]                      
Deferred revenue $ 923,000     $ 923,000   $ 923,000       $ 1,700,000  
Sales discount percentage 2.00%     2.00%   2.00%          
Sales discount term           30 days          
Trade receivables, credit period           30 days          
Number of tranches for private placement transaction | Tranche 2     2   2          
Accounts receivable written off $ 0     $ 0   $ 0          
Warrants expiration date           Feb. 27, 2015          
Warrants exercised | shares           1,844,585          
Warrants expired | shares   6,242,803                  
Warrant derivative liability     $ 100,000                
Derivative liability fair value assumptions, risk-free rate     0.04%                
Derivative liability fair value assumptions, term     1 month 28 days                
Derivative liability fair value assumptions, dividend yield     0.00%                
Derivative liability fair value assumptions, volatility rate     79.00%                
Gain (loss) on change in fair value of derivative liability       (230,000) $ 4,466,000 $ (366,000) $ 11,870,000        
Number of operating segments | Segment           1          
Embedded Derivative Financial Instruments                      
Significant Accounting Policies [Line Items]                      
Gain (loss) on change in fair value of derivative liability (300,000)         $ 470,000 5,600,000        
Maximum repayment of future revenue and receivables                     $ 150,000,000
Long term debt redemption feature $ 5,100,000   $ 4,800,000 $ 5,100,000   5,100,000          
Preferred Stock Purchase Option                      
Significant Accounting Policies [Line Items]                      
Gain (loss) on change in fair value of derivative liability           $ (946,000)          
Derivative liability at fair value               $ 900,000      
Warrants Issued October 2009                      
Significant Accounting Policies [Line Items]                      
Warrants outstanding | shares 0     0   0          
Gain (loss) on change in fair value of derivative liability           $ 110,000 $ 6,270,000        
Top Three Customers | Gross Product Sales | Customer Concentration Risk                      
Significant Accounting Policies [Line Items]                      
Concentration risk percentage           95.00% 95.00%        
Top Three Customers | Accounts Receivable | Customer Concentration Risk                      
Significant Accounting Policies [Line Items]                      
Concentration risk percentage           95.00% 96.00%        
Prior To Agreement                      
Significant Accounting Policies [Line Items]                      
Warrants expiration date           Oct. 16, 2014          
Convertible Debt                      
Significant Accounting Policies [Line Items]                      
Gain (loss) on change in fair value of derivative liability           $ 800,000          
Derivative liability at fair value                 $ 3,500,000    
Convertible Debt | 2014 Notes                      
Significant Accounting Policies [Line Items]                      
Convertible senior notes, discount                 $ 27,900,000    
Derivative liability fair value assumptions, risk-free rate 2.70%   2.70%                
Derivative liability fair value assumptions, dividend yield 22.90%   24.80%                
Derivative liability fair value assumptions, volatility rate 83.00%   82.00%                
Gain (loss) on change in fair value of derivative liability $ 800,000                    
Long term debt redemption feature 1,800,000   $ 2,600,000 $ 1,800,000   1,800,000          
Convertible Debt | 2012 Notes                      
Significant Accounting Policies [Line Items]                      
Convertible senior notes, discount 0   0 0   0          
Convertible Debt | Non Cash | 2014 Notes                      
Significant Accounting Policies [Line Items]                      
Convertible senior notes, discount $ 23,900,000   $ 28,200,000 $ 23,900,000   $ 23,900,000          
Maximum                      
Significant Accounting Policies [Line Items]                      
Short term highly liquid instruments, maturity date           90 days          
Warrants outstanding | shares     8,087,388                
Maximum | Embedded Derivative Financial Instruments                      
Significant Accounting Policies [Line Items]                      
Derivative liability fair value assumptions, term 5 years 4 months 24 days   3 years 7 months 6 days                
Derivative liability fair value assumption, coupon rate 12.50%   10.80%                
Derivative liability fair value assumptions, market yields 18.80%   16.80%                
Minimum | Embedded Derivative Financial Instruments                      
Significant Accounting Policies [Line Items]                      
Derivative liability fair value assumptions, term 2 years 3 months 18 days   2 years 3 months 18 days                
Derivative liability fair value assumption, coupon rate 8.90%   9.80%                
Derivative liability fair value assumptions, market yields 10.50%   10.00%