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Warrants and Warrant Derivative Liability - Additional Information (Detail)
$ / shares in Units, $ in Thousands
 9 Months Ended 12 Months Ended
Feb. 27, 2015
shares
Oct. 16, 2009
USD ($)
$ / shares
shares
Sep. 30, 2015
USD ($)
shares
Sep. 30, 2014
USD ($)
Dec. 31, 2014
USD ($)
shares
Derivative [Line Items]          
Common stock issued under private placement, value | $     $ 57,853    
Common stock issued under private placement, net proceeds | $     $ 52,800    
Warrants expiration date     Feb. 27, 2015    
Warrants exercised     1,844,585    
Proceed from exercise of warrants | $     $ 2,713 $ 1,651  
Warrants expired 6,242,803        
Maximum          
Derivative [Line Items]          
Warrants outstanding         8,087,388
Prior To Agreement          
Derivative [Line Items]          
Warrants expiration date     Oct. 16, 2014    
Warrants Issued October 2009          
Derivative [Line Items]          
Warrants outstanding     0    
Warrants expiration date     Feb. 27, 2015    
Warrants exercised     1,844,585    
Proceed from exercise of warrants | $     $ 2,700    
Warrants expired 6,242,803        
Warrants Issued October 2009 | Maximum          
Derivative [Line Items]          
Warrants outstanding         8,087,388
Warrants Issued October 2009 | Prior To Agreement          
Derivative [Line Items]          
Warrants expiration date     Oct. 16, 2014    
Warrants Issued July 2009          
Derivative [Line Items]          
Warrants outstanding     0   0
Warrants exercised         1,684,888
Proceed from exercise of warrants | $         $ 1,700
October 2009 Private Placement          
Derivative [Line Items]          
Common stock issued under private placement, value | $   $ 70,000      
Common stock issued under private placement, net proceeds | $   $ 62,300      
Common stock issued under private placement, shares   66,400,000      
Number of shares that each ADS represents   1      
Common stock issued under private placement, price per share | $ / shares   $ 1.00      
October 2009 Private Placement | Warrants issued to three former officers          
Derivative [Line Items]          
Number of warrants issued   900,000      
October 2009 Private Placement | Bridge Loan          
Derivative [Line Items]          
Bridge notes converted in conjunction with the private placement, amount | $   $ 3,600      
Common stock issued under private placement, shares   4,000,000      
Number of shares that each ADS represents   1      
Bridge notes converted in conjunction with the private placement, price per share | $ / shares   $ 0.90      
October 2009 Private Placement | Warrants Issued October 2009          
Derivative [Line Items]          
Number of warrants issued   35,200,000      
Description of pricing variability feature and classification of warrants     The warrants issued in connection with the October 2009 financing contained a pricing variability feature which provided for an increase to the exercise price if the exchange rate between the U.S. dollar and British pound adjusts such that the warrants could be exercised at a price less than the £0.5 par value of the common stock - that is, if the exchange rate exceeded U.S. $3.00 per £1.0 sterling. Due to the potential variable nature of the exercise price, the warrants are not considered to be indexed to the Company’s common stock. Accordingly, the warrants do not qualify for the exception to classify the warrants within equity and are classified as a derivative liability.    
October 2009 Private Placement | Warrants Issued October 2009 | Maximum          
Derivative [Line Items]          
Warrants issued, number of shares called by the warrant   36,100,000      
October 2009 Private Placement | Warrants Issued October 2009 | American Depositary Share          
Derivative [Line Items]          
Warrant term   5 years      
Warrants issued, number of shares called by a warrant   0.5      
Exercise price of the warrants | $ / shares   $ 1.50      
October 2009 Private Placement | Warrants Issued October 2009 | Bridge Loan | American Depositary Share          
Derivative [Line Items]          
Warrant term   5 years      
Warrants issued, number of shares called by a warrant   0.5      
Exercise price of the warrants | $ / shares   $ 1.50