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Co-Promotion Agreement - Additional Information (Detail)
$ in Thousands
9 Months Ended
Sep. 30, 2015
USD ($)
Employee
Dec. 31, 2014
USD ($)
Co-Promotion Agreement [Line Items]    
Promotion fee as a percentage gross margin From the high single digits in 2014 to the low twenty percent level in 2018.  
Net payables $ 17,899 $ 8,525
Kowa Pharmaceuticals America    
Co-Promotion Agreement [Line Items]    
Net receivable   $ 600
Net payables $ 400  
Kowa Pharmaceuticals America | Minimum    
Co-Promotion Agreement [Line Items]    
Number of sales representatives | Employee 250