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v3.3.1.900

Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Product revenue, net | $ 80,987 | $ 54,202 | $ 26,351
Licensing revenue | 769 |  |
Total revenue, net | 81,756 | 54,202 | 26,351
Less: Cost of goods sold | 27,875 | 20,485 | 11,912
Gross margin | 53,881 | 33,717 | 14,439
Operating expenses: |  |  |
Selling, general and administrative | 101,041 | 79,346 | 123,795
Research and development | 51,062 | 50,326 | 72,750
Total operating expenses | 152,103 | 129,672 | 196,545
Operating loss | (98,222) | (95,955) | (182,106)
(Loss) gain on change in fair value of derivative liabilities | (1,106) | 13,472 | 47,710
Gain on extinguishment of debt | 1,314 | 38,034 |
Interest expense | (20,180) | (18,575) | (34,179)
Interest income | 132 | 96 | 343
Other (expense) income, net | (228) | 3,727 | (1,189)
Loss from operations before taxes | (118,290) | (59,201) | (169,421)
Benefit from income taxes | 3,086 | 2,837 | 3,194
Net loss | (115,204) | (56,364) | (166,227)
Preferred stock purchase option | (868) |  |
Preferred stock beneficial conversion features | (32,987) |  |
Net loss applicable to common shareholders | $ (149,059) | $ (56,364) | $ (166,227)
Loss per share: |  |  |
Basic | $ (0.83) | $ (0.32) | $ (1.03)
Diluted | $ (0.83) | $ (0.36) | $ (1.28)
Weighted average shares: |  |  |
Basic | 180,654 | 173,719 | 161,022
Diluted | 180,654 | 173,824 | 167,070

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