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Development, Commercialization and Supply Agreement - Additional Information (Detail) - USD ($)
12 Months Ended
Feb. 26, 2015
Dec. 31, 2015
License And Collaboration Agreements [Line Items]    
Licensing revenue   $ 769,000
Eddingpharm    
License And Collaboration Agreements [Line Items]    
Non-refundable up-front received $ 15,000,000  
Deferred revenue   $ 14,200,000
Licensing agreement term   16 years
Eddingpharm | Maximum    
License And Collaboration Agreements [Line Items]    
Additional upfront payment eligible to receive based on development, regulatory and sales Milestone $ 154,000,000  
Eddingpharm | Up-front Payment    
License And Collaboration Agreements [Line Items]    
Licensing revenue   $ 800,000