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Co-Promotion Agreement - Additional Information (Detail) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2016 USD ($) Employee | Dec. 31, 2016 | Dec. 31, 2015 USD ($)
Co-Promotion Agreement [Line Items] |  |  |
Accrued expenses and other current liabilities | $ | $ 24,551 |  | $ 24,226
Co-Promotion Agreement (the Agreement) |  |  |
Co-Promotion Agreement [Line Items] |  |  |
Promotion fee as a percentage of gross margin |  |  | 15.00%
Promotion fee as a percentage gross margin | Scheduled to increase to low twenty percent levels in 2017 and 2018, subject to certain adjustments. |  |
Co-Promotion Agreement (the Agreement) | Scenario, Forecast |  |  |
Co-Promotion Agreement [Line Items] |  |  |
Promotion fee as a percentage of gross margin |  | 19.00% |
Co-Promotion Agreement (the Agreement) | Kowa Pharmaceuticals America |  |  |
Co-Promotion Agreement [Line Items] |  |  |
Number of sales representatives | Employee | 250 |  |
Accrued expenses and other current liabilities | $ | $ 1,100 |  | $ 2,500
Co-Promotion Agreement (the Agreement) | Kowa Pharmaceuticals America | Minimum |  |  |
Co-Promotion Agreement [Line Items] |  |  |
Number of sales representatives | Employee | 250 |  |

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- Definition Co-Promotion Agreement [Line Items] + References No definition available. + Details
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- Definition Percentage of Gross Margin, Payable for Promotion Agreement + References No definition available. + Details
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- Definition Amount of obligations incurred and payable, pertaining to costs that are statutory in nature, incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include, but not limited to, taxes, interest, rent and utilities. Also includes the aggregate carrying amount of liabilities not separately disclosed. + References No definition available. + Details
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