Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2016

Summarize Activity of the Net Product Revenue Allowance and Reserve Categories

The following tables summarize activity in each of the net product revenue allowance and reserve categories described above for the three months ended March 31, 2016 and 2015 (in thousands):


	Trade Allowances			Rebates, Chargebacks and Discounts			Product Returns			Other Incentives			Total
Balance at December 31, 2015	$	4,296		$	9,881		$	535		$	1,084		$	15,796
Provision related to current period sales		4,218			11,455			107			2,529			18,309
Provision related to prior period sales		(274	)		(435	)		—			—			(709	)
Credits/payments made for current period sales		(1,463	)		(1,228	)		—			(322	)		(3,013	)
Credits/payments made for prior period sales		(2,734	)		(6,418	)		(82	)		(1,284	)		(10,518	)

Balance at March 31, 2016	$	4,043		$	13,255		$	560		$	2,007		$	19,865


	Trade Allowances			Rebates, Chargebacks and Discounts			Product Returns		Other Incentives			Total
Balance at December 31, 2014	$	2,207		$	3,610		$	481	$	792		$	7,090
Provision related to current period sales		2,756			5,145			127		1,717			9,745
Provision related to prior period sales		—			74			—		—			74
Credits/payments made for current period sales		(462	)		(1,288	)		—		(1,085	)		(2,835	)
Credits/payments made for prior period sales		(1,555	)		(3,367	)		—		(607	)		(5,529	)

Balance at March 31, 2015	$	2,946		$	4,174		$	608	$	817		$	8,545

Summarizes the Impact of Accounts Receivable Reserves on Gross Trade Accounts Receivable

The following table summarizes the impact of accounts receivable reserves on the gross trade accounts receivable balances as of March 31, 2016 and December 31, 2015 (in thousands):


	March 31, 2016			December 31, 2015
Gross trade accounts receivable	$	19,292		$	18,270
Trade allowances		(4,043	)		(4,296	)
Chargebacks		(230	)		(148	)

Accounts receivable, net	$	15,019		$	13,826

Estimated Useful Lives

The estimated useful lives, by asset classification, are as follows:


Asset Classification		Useful Lives
Computer equipment and software		3 - 5 years
Furniture and fixtures		5 years
Leasehold improvements		Lesser of useful life or lease term

Net Loss and the Number of Shares Used to Compute Basic and Diluted Net Loss per Share

The calculation of net loss and the number of shares used to compute basic and diluted net loss per share for the three months ended March 31, 2016 and 2015 are as follows:


In thousands	March 31, 2016			March 31, 2015
Net loss	$	(29,771	)	$	(31,126	)
Preferred stock purchase option (see Note 8)		—			(868	)

Net loss applicable to common shareholders—basic		(29,771	)		(31,994	)
Gain on warrant derivative liability		—			(119	)

Net loss—diluted		(29,771	)		(32,113	)
Net loss per share—basic		(0.16	)		(0.18	)


In thousands	March 31, 2016			March 31, 2015
Weighted average shares outstanding—basic		184,052			175,582
Weighted average shares outstanding—diluted		184,052			175,582
Net loss per share—diluted	$	(0.16	)	$	(0.18	)

Anti-Dilutive Securities Not Included in the Computation of Net Loss or Earnings per Share

For the three months ended March 31, 2016 and 2015, the following potentially dilutive securities were not included in the computation of net loss per share because the effect would be anti-dilutive:


In thousands	March 31, 2016		March 31, 2015
Stock options		20,807		12,078
Restricted stock and restricted stock units		10,673		4,071
Exchangeable senior notes (if converted)		59,407		49,215
Preferred stock (if converted)		32,818		35,215

Assets and Liability Measured at Fair Value on a Recurring Basis

The following tables present information about the Company’s assets and liabilities as of March 31, 2016 and December 31, 2015 that are measured at fair value on a recurring basis and indicate the fair value hierarchy of the valuation techniques the Company utilized to determine such fair value:


	March 31, 2016
*In thousands*	Total		Level 1		Level 2		Level 3
Asset:
Cash equivalents—money markets	$	14,195	$	14,195	$	—	$	—


Liabilities:
Long-term debt derivative liabilities	$	9,420	$	—	$	—	$	9,420


	December 31, 2015
*In thousands*	Total		Level 1		Level 2		Level 3
Asset:
Cash equivalents—money markets	$	14,184	$	14,184	$	—	$	—


Liabilities:
Long-term debt derivative liabilities	$	8,170	$	—	$	—	$	8,170

Carrying Amounts and Estimated Fair Values of Debt Instruments

The carrying amounts and the estimated fair values of debt instruments as of March 31, 2016 and December 31, 2015 are as follows:


	March 31, 2016				December 31, 2015
In thousands	Carrying Value		Estimated Fair Value		Carrying Value		Estimated Fair Value
Long-term debt—December 2012 financing	$	92,016	$	85,700	$	91,512	$	87,700
2012 Notes		15,107		14,050		15,107		13,637
2014 Notes		96,257		95,878		94,599		108,034
2015 Notes		27,339		25,247		27,028		28,448

Change in Fair Value of Derivative Liabilities

The change in the fair value of derivative liabilities for the three months ended March 31, 2016 and 2015 is as follows (in thousands):


	October 2009 Warrants		Long-Term Debt Derivative Liabilities		Preferred Stock Purchase Option		Totals
Balance at December 31, 2015	$	—	$	8,170	$	—	$	8,170
Loss on change in fair value of derivative liabilities		—		1,250		—		1,250

Balance at March 31, 2016	$	—	$	9,420	$	—	$	9,420


	October 2009 Warrants			Long-Term Debt Derivative Liabilities			Preferred Stock Purchase Option			Totals
Balance at December 31, 2014	$	119		$	7,400		$	—		$	7,519
Record derivative liability		—			—			868			868
(Gain) loss on change in fair value of derivative liabilities		(110	)		(1,300	)		946			(464	)
Compensation income for change in fair value of warrants issued to former employees		(9	)		—			—			(9	)
Transfer derivative liability to equity		—			—			(1,814	)		(1,814	)

Balance at March 31, 2015	$	—		$	6,100		$	—		$	6,100