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Summarizes Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance $ 15,796 $ 7,090
Provision related to current period sales 18,309 9,745
Provision related to prior period sales (709) 74
Credits/payments made for current period sales (3,013) (2,835)
Credits/payments made for prior period sales (10,518) (5,529)
Ending balance 19,865 8,545
Trade Receivables    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 4,296 2,207
Provision related to current period sales 4,218 2,756
Provision related to prior period sales (274)  
Credits/payments made for current period sales (1,463) (462)
Credits/payments made for prior period sales (2,734) (1,555)
Ending balance 4,043 2,946
Rebates Chargebacks And Discounts    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 9,881 3,610
Provision related to current period sales 11,455 5,145
Provision related to prior period sales (435) 74
Credits/payments made for current period sales (1,228) (1,288)
Credits/payments made for prior period sales (6,418) (3,367)
Ending balance 13,255 4,174
Allowance for Sales Returns    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 535 481
Provision related to current period sales 107 127
Credits/payments made for prior period sales (82)  
Ending balance 560 608
Other Incentive Programs    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 1,084 792
Provision related to current period sales 2,529 1,717
Credits/payments made for current period sales (322) (1,085)
Credits/payments made for prior period sales (1,284) (607)
Ending balance $ 2,007 $ 817