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Condensed Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Product revenue, net $ 32,815 $ 17,707 $ 58,122 $ 33,265
Licensing revenue 296   532 375
Total revenue, net 33,111 17,707 58,654 33,640
Less: Cost of goods sold 8,861 6,381 15,757 12,008
Gross margin 24,250 11,326 42,897 21,632
Operating expenses:        
Selling, general and administrative 26,066 26,054 54,086 50,795
Research and development 12,578 12,009 26,308 24,623
Total operating expenses 38,644 38,063 80,394 75,418
Operating loss (14,394) (26,737) (37,497) (53,786)
Gain (loss) on change in fair value of derivative liabilities 5,810 (600) 4,560 (136)
Interest expense, net (5,616) (4,807) (11,202) (9,692)
Other (expense) income, net (182) 95 (303) (33)
Loss from operations before taxes (14,382) (32,049) (44,442) (63,647)
Benefit from income taxes 1,028 537 1,317 1,009
Net loss (13,354) (31,512) (43,125) (62,638)
Preferred stock purchase option       (868)
Preferred stock beneficial conversion feature   (31,341)   (31,341)
Net loss applicable to common shareholders $ (13,354) $ (62,853) $ (43,125) $ (94,847)
Loss per share:        
Basic $ (0.07) $ (0.35) $ (0.23) $ (0.53)
Diluted $ (0.07) $ (0.35) $ (0.23) $ (0.53)
Weighted average shares:        
Basic 184,471 180,464 184,262 178,036
Diluted 184,471 180,464 184,262 178,036