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Summarizes Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance $ 15,796 $ 7,090
Provision related to current period sales 71,318 37,944
Provision related to prior period sales (489) (244)
Credits/payments made for current period sales (40,110) (25,143)
Credits/payments made for prior period sales (14,203) (6,383)
Ending balance 32,312 13,264
Trade Receivables    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 4,296 2,207
Provision related to current period sales 15,823 10,104
Provision related to prior period sales (87) (174)
Credits/payments made for current period sales (11,086) (6,729)
Credits/payments made for prior period sales (4,180) (2,043)
Ending balance 4,766 3,365
Rebates Chargebacks And Discounts    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 9,881 3,610
Provision related to current period sales 46,553 21,633
Provision related to prior period sales (402) (70)
Credits/payments made for current period sales (22,236) (14,194)
Credits/payments made for prior period sales (8,492) (3,522)
Ending balance 25,304 7,457
Allowance for Sales Returns    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 535 481
Provision related to current period sales 403 231
Credits/payments made for prior period sales (247) (26)
Ending balance 691 686
Other Incentive Programs    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 1,084 792
Provision related to current period sales 8,539 5,976
Credits/payments made for current period sales (6,788) (4,220)
Credits/payments made for prior period sales (1,284) (792)
Ending balance $ 1,551 $ 1,756