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Co-Promotion Agreement - Additional Information (Detail) - USD ($) $ in Thousands | 9 Months Ended |
--- | --- | ---
Sep. 30, 2017 | Dec. 31, 2016
Co Promotion Agreement [Line Items] |  |
Accrued expenses and other current liabilities | $ 51,627 | $ 37,720
Co-Promotion Agreement (the Agreement) |  |
Co Promotion Agreement [Line Items] |  |
Promotion fee as a percentage of gross margin | 18.00% |
Promotion fee as a percentage gross margin | scheduled, as amended, to be approximately eighteen percent (18%) in 2017, partially offset by certain other refinements |
Co-Promotion Agreement (the Agreement) | Kowa Pharmaceuticals America |  |
Co Promotion Agreement [Line Items] |  |
Agreement amended date | Jul. 25, 2017 |
Accrued expenses and other current liabilities | $ 6,000 | $ 2,500

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