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Significant Accounting Policies (Tables) | 9 Months Ended
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Sep. 30, 2017
Accounting Policies [Abstract] |
Summarize Activity of the Net Product Revenue Allowance and Reserve Categories | The following tables summarize activity in each of the net product revenue allowance and reserve categories described above for the nine months ended September 30, 2017 and 2016:
In thousands |  | Trade Allowances |  |  | Rebates, Chargebacks and Discounts |  |  | Product Returns |  |  | Other Incentives |  |  | Total |
Balance as of December 31, 2016 |  | $ | 3,743 |  |  | $ | 20,915 |  |  | $ | 859 |  |  | $ | 1,681 |  |  | $ | 27,198 |
Provision related to current period sales |  |  | 24,780 |  |  |  | 87,499 |  |  |  | 1,496 |  |  |  | 10,796 |  |  |  | 124,571 |
Provision related to prior period sales |  |  | (297 | ) |  |  | (841 | ) |  |  | — |  |  |  | (82 | ) |  |  | (1,220 | )
Credits/payments made for current period sales |  |  | (11,061 | ) |  |  | (62,014 | ) |  |  | (391 | ) |  |  | (8,834 | ) |  |  | (82,300 | )
Credits/payments made for prior period sales |  |  | (3,107 | ) |  |  | (16,722 | ) |  |  | (24 | ) |  |  | (1,770 | ) |  |  | (21,623 | )
Balance as of September 30, 2017 |  | $ | 14,058 |  |  | $ | 28,837 |  |  | $ | 1,940 |  |  | $ | 1,791 |  |  | $ | 46,626 |
In thousands |  | Trade Allowances |  |  | Rebates, Chargebacks and Discounts |  |  | Product Returns |  |  | Other Incentives |  |  | Total |
Balance as of December 31, 2015 |  | $ | 4,296 |  |  | $ | 9,881 |  |  | $ | 535 |  |  | $ | 1,084 |  |  | $ | 15,796 |
Provision related to current period sales |  |  | 15,823 |  |  |  | 46,553 |  |  |  | 403 |  |  |  | 8,539 |  |  |  | 71,318 |
Provision related to prior period sales |  |  | (87 | ) |  |  | (402 | ) |  |  | — |  |  |  | — |  |  |  | (489 | )
Credits/payments made for current period sales |  |  | (11,086 | ) |  |  | (22,236 | ) |  |  | — |  |  |  | (6,788 | ) |  |  | (40,110 | )
Credits/payments made for prior period sales |  |  | (4,180 | ) |  |  | (8,492 | ) |  |  | (247 | ) |  |  | (1,284 | ) |  |  | (14,203 | )
Balance as of September 30, 2016 |  | $ | 4,766 |  |  | $ | 25,304 |  |  | $ | 691 |  |  | $ | 1,551 |  |  | $ | 32,312 |
Summarizes the Impact of Accounts Receivable Reserves on Gross Trade Accounts Receivable | The following table summarizes the impact of accounts receivable reserves on the gross trade accounts receivable balances as of September 30, 2017 and December 31, 2016:
In thousands |  | September 30, 2017 |  |  | December 31, 2016 |
Gross trade accounts receivable |  | $ | 49,054 |  |  | $ | 24,127 |
Trade allowances |  |  | (14,058 | ) |  |  | (3,743 | )
Chargebacks |  |  | (374 | ) |  |  | (387 | )
Allowance for doubtful accounts |  |  | (12 | ) |  |  | (12 | )
Accounts receivable, net |  | $ | 34,610 |  |  | $ | 19,985 |
Estimated Useful Lives | The estimated useful lives, by asset classification, are as follows:
Asset Classification |  | Useful Lives
Computer equipment and software |  | 3 - 5 years
Furniture and fixtures |  | 5 years
Leasehold improvements |  | Lesser of useful life or lease term
Net Loss and the Number of Shares Used to Compute Basic and Diluted Net Loss per Share | The calculation of net loss and the number of shares used to compute basic and diluted net loss per share for the three and nine months ended September 30, 2017 and 2016 are as follows:
|  | Three months ended September 30, |  |  | Nine months ended September 30, |
In thousands |  | 2017 |  |  | 2016 |  |  | 2017 |  |  | 2016 |
Net loss—basic and diluted |  | $ | (10,825 | ) |  | $ | (15,772 | ) |  | $ | (45,400 | ) |  | $ | (58,897 | )
Weighted average shares outstanding—basic and diluted |  |  | 270,803 |  |  |  | 209,149 |  |  |  | 270,566 |  |  |  | 192,618 |
Net loss per share—basic and diluted |  | $ | (0.04 | ) |  | $ | (0.08 | ) |  | $ | (0.17 | ) |  | $ | (0.31 | )
Anti-Dilutive Securities Not Included in the Computation of Net Loss or Earnings per Share | For the three and nine months ended September 30, 2017 and 2016, the following potentially dilutive securities were not included in the computation of net loss per share because the effect would be anti-dilutive:
|  | Three months ended September 30, |  |  | Nine months ended September 30, |
In thousands |  | 2017 |  |  | 2016 |  |  | 2017 |  |  | 2016 |
Stock options |  |  | 23,631 |  |  |  | 21,241 |  |  |  | 23,631 |  |  |  | 21,241 |
Restricted stock and restricted stock units |  |  | 11,887 |  |  |  | 10,346 |  |  |  | 11,887 |  |  |  | 10,346 |
Exchangeable senior notes (if converted) |  |  | 7,716 |  |  |  | 1,714 |  |  |  | 7,716 |  |  |  | 1,714 |
Preferred stock (if converted) |  |  | 32,818 |  |  |  | 32,818 |  |  |  | 32,818 |  |  |  | 32,818 |
Assets and Liability Measured at Fair Value on a Recurring Basis | The following tables present information about the Company’s assets and liabilities as of September 30, 2017 and December 31, 2016 that are measured at fair value on a recurring basis and indicate the fair value hierarchy of the valuation techniques the Company utilized to determine such fair value:
|  | September 30, 2017 |
In thousands |  | Total |  |  | Level 1 |  |  | Level 2 |  |  | Level 3 |
Asset: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash equivalents—money markets |  | $ | 9,296 |  |  | $ | 9,296 |  |  | $ | — |  |  | $ | — |
|  | December 31, 2016 |
In thousands |  | Total |  |  | Level 1 |  |  | Level 2 |  |  | Level 3 |
Asset: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Cash equivalents—money markets |  | $ | 14,238 |  |  | $ | 14,238 |  |  | $ | — |  |  | $ | — |
Carrying Amounts and Estimated Fair Values of Debt Instruments | The carrying amounts of cash, cash equivalents, accounts payable and accrued liabilities approximate fair value because of their short-term nature. The carrying amounts and the estimated fair values of debt instruments as of September 30, 2017 and December 31, 2016 are as follows:
|  | September 30, 2017 |  |  | December 31, 2016 |
In thousands |  | Carrying Value |  |  | Estimated Fair Value |  |  | Carrying Value |  |  | Estimated Fair Value |
Current portion of long-term debt from royalty-bearing instrument, net of accrued interest |  | $ | 19,624 |  |  |  |  |  |  | $ | 8,437 |  |  |  |  |
Long-term debt from royalty-bearing instrument |  |  | 75,559 |  |  |  |  |  |  |  | 85,155 |  |  |  |  |
Total long-term debt from royalty-bearing instrument |  | $ | 95,183 |  |  | $ | 90,400 |  |  | $ | 93,592 |  |  | $ | 90,500 |
2012 Notes |  |  | — |  |  |  | — |  |  |  | 15,107 |  |  |  | 15,174 |
2017 Notes |  |  | 28,938 |  |  |  | 34,000 |  |  |  | — |  |  |  | — |

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