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Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Income Statement [Abstract]
Product revenue, net	$ 43,777	$ 34,344
Licensing revenue	142	293
Total revenue, net	43,919	34,637
Less: Cost of goods sold	10,648	8,198
Gross margin	33,271	26,439
Operating expenses:
Selling, general and administrative	43,407	34,171
Research and development	11,762	10,823
Total operating expenses	55,169	44,994
Operating loss	(21,898)	(18,555)
Interest expense, net	(2,252)	(2,381)
Other income (expense), net	55	(5)
Loss from operations before taxes	(24,095)	(20,941)
Net loss	$ (24,095)	$ (20,941)
Loss per share:
Basic	$ (0.08)	$ (0.08)
Diluted	$ (0.08)	$ (0.08)
Weighted average shares:
Basic	285,207	270,163
Diluted	285,207	270,163

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