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Summarize Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance $ 48,093 $ 27,198
Provision related to current period sales 45,860 30,426
Provision related to prior period sales (704) (1,082)
Credits/payments made for current period sales (13,161) (4,416)
Credits/payments made for prior period sales (24,651) (20,262)
Ending balance 55,437 31,864
Trade Allowances    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 12,035 3,743
Provision related to current period sales 8,506 6,621
Provision related to prior period sales (200) (298)
Credits/payments made for current period sales (875) (2,357)
Credits/payments made for prior period sales (1,336) (3,107)
Ending balance 18,130 4,602
Rebates, Chargebacks and Discounts    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 32,064 20,915
Provision related to current period sales 32,947 19,670
Provision related to prior period sales (435) (702)
Credits/payments made for current period sales (10,487) (727)
Credits/payments made for prior period sales (20,994) (15,376)
Ending balance 33,095 23,780
Product Returns    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 1,887 859
Provision related to current period sales 222 1,028
Credits/payments made for prior period sales (25) (9)
Ending balance 2,084 1,878
Other Incentives    
Valuation and Qualifying Accounts Disclosure [Line Items]    
Beginning balance 2,107 1,681
Provision related to current period sales 4,185 3,107
Provision related to prior period sales (69) (82)
Credits/payments made for current period sales (1,799) (1,332)
Credits/payments made for prior period sales (2,296) (1,770)
Ending balance $ 2,128 $ 1,604