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Summarize Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2018 | Jun. 30, 2017
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | $ 48,093 | $ 27,198
Provision related to current period sales | 106,853 | 76,790
Provision related to prior period sales | (1,305) | (1,221)
Credits/payments made for current period sales | (56,177) | (45,210)
Credits/payments made for prior period sales | (34,647) | (21,623)
Ending balance | 62,817 | 35,934
Trade Allowances |  |
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 12,035 | 3,743
Provision related to current period sales | 19,077 | 15,685
Provision related to prior period sales | (400) | (298)
Credits/payments made for current period sales | (9,097) | (5,496)
Credits/payments made for prior period sales | (5,282) | (3,107)
Ending balance | 16,333 | 10,527
Rebates, Chargebacks and Discounts |  |
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 32,064 | 20,915
Provision related to current period sales | 78,051 | 53,078
Provision related to prior period sales | (836) | (841)
Credits/payments made for current period sales | (40,547) | (34,771)
Credits/payments made for prior period sales | (27,028) | (16,722)
Ending balance | 41,704 | 21,659
Product Returns |  |
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 1,887 | 859
Provision related to current period sales | 491 | 1,259
Credits/payments made for current period sales |  | (21)
Credits/payments made for prior period sales | (40) | (24)
Ending balance | 2,338 | 2,073
Other Incentives |  |
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 2,107 | 1,681
Provision related to current period sales | 9,234 | 6,768
Provision related to prior period sales | (69) | (82)
Credits/payments made for current period sales | (6,533) | (4,922)
Credits/payments made for prior period sales | (2,297) | (1,770)
Ending balance | $ 2,442 | $ 1,675

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