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Nature of Business and Basis of Presentation - Additional Information (Detail) $ in Thousands |  | 6 Months Ended |
--- | --- | --- | ---
Jan. 20, 2017 USD ($) | Jun. 30, 2018 USD ($) Patient Employee Segment | Dec. 31, 2017 USD ($)
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |
REDUCE-IT study, number of patients enrolled and randomized | Patient |  | 8,175 |
Number of sales professionals | Employee |  | 170 |
Number of operating segments | Segment |  | 1 |
Total current assets |  | $ 196,137 | $ 153,270
Cash and cash equivalents |  | 102,257 | $ 73,637
Convertible Debt | 2017 Notes |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |
Convertible senior notes, principal amount | $ 30,000 | $ 30,000 |
Convertible senior notes, due date | 2047 |  |
Convertible senior notes, stated interest rate | 3.50% |  |
Convertible senior notes, repurchase price at option of the issuer | 100.00% |  |

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