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Commitments and Contingencies - Additional Information (Detail) - 9 months ended Sep. 30, 2018 | USD ($) | GBP (£)
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Further Indication for AMR101 | Marketing Approval In Europe |  |
Commitments And Contingencies Disclosure [Line Items] |  |
Potential aggregate stock or cash payment | $ 9,800,000 | £ 7,500,000
Further Indication for AMR101 | Potential Marketing Approval 1 |  |
Commitments And Contingencies Disclosure [Line Items] |  |
Potential aggregate stock or cash payment | 6,500,000 | 5,000,000
Further Indication for AMR101 | Potential Marketing Approval 2 |  |
Commitments And Contingencies Disclosure [Line Items] |  |
Potential aggregate stock or cash payment | 6,500,000 | 5,000,000
Further Indication for AMR101 | Maximum |  |
Commitments And Contingencies Disclosure [Line Items] |  |
Potential aggregate stock or cash payment | 13,000,000 | £ 10,000,000
Nisshin |  |
Commitments And Contingencies Disclosure [Line Items] |  |
Royalty, milestone or minimum purchase commitments | $ 0 |

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- Definition Commitments and contingencies disclosure. + References No definition available. + Details
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- Definition Royalty, milestone or minimum purchase commitments. + References No definition available. + Details
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- Definition The amount the entity has committed to make for future royalty guarantees. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 928 -SubTopic 440 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6473578&loc=d3e63223-108013 + Details
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- Details
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- Details
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- Details
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