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Nature of Business and Basis of Presentation - Additional Information (Detail) |  |  | 9 Months Ended |
--- | --- | --- | --- | ---
Nov. 02, 2018 USD ($) shares | Jan. 20, 2017 USD ($) | Sep. 30, 2018 USD ($) shares Patient Employee Segment | Dec. 31, 2017 USD ($)
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |
REDUCE-IT study, number of patients enrolled and randomized | Patient |  |  | 8,175 |
Number of sales professionals | Employee |  |  | 170 |
Number of operating segments | Segment |  |  | 1 |
Proposed number of sales professionals | Employee |  |  | 400 |
Total current assets |  |  | $ 202,402,000 | $ 153,270,000
Cash and cash equivalents |  |  | 81,892,000 | 73,637,000
Accounts receivable, net |  |  | 47,648,000 | 45,318,000
Other receivables |  |  | 25,654,000 |
Convertible Debt | 2017 Notes |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |
Convertible senior notes, principal amount |  | $ 30,000,000 | $ 30,000,000 |
Convertible senior notes, due date |  | 2047 |  |
Convertible senior notes, stated interest rate |  | 3.50% |  |
Convertible senior notes, repurchase price at option of the issuer |  | 100.00% |  |
Convertible senior notes, total ADS into which the debt is exchangeable | shares |  |  | 7,716,048 |
Convertible senior notes, interest obligations |  |  | $ 200,000 | $ 200,000
Convertible Debt | 2017 Notes | Scenario Forecast |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |
Convertible senior notes, outstanding amount | $ 0 |  |  |
Convertible senior notes, interest obligations | $ 0 |  |  |
Convertible Debt | 2017 Notes | Scenario Forecast | American Depositary Shares |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |
Convertible senior notes, total ADS into which the debt is exchangeable | shares | 7,716,048 |  |  |

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