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Summarize Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2018 | Sep. 30, 2017
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | $ 48,093 | $ 27,198
Provision related to current period sales | 175,167 | 124,571
Provision related to prior period sales | (1,565) | (1,220)
Credits/payments made for current period sales | (106,961) | (82,300)
Credits/payments made for prior period sales | (43,617) | (21,623)
Ending balance | 71,117 | 46,626
Trade Allowances |  |
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 12,035 | 3,743
Provision related to current period sales | 30,814 | 24,780
Provision related to prior period sales | (660) | (297)
Credits/payments made for current period sales | (15,908) | (11,061)
Credits/payments made for prior period sales | (11,657) | (3,107)
Ending balance | 14,624 | 14,058
Rebates, Chargebacks and Discounts |  |
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 32,064 | 20,915
Provision related to current period sales | 128,905 | 87,499
Provision related to prior period sales | (836) | (841)
Credits/payments made for current period sales | (76,015) | (62,014)
Credits/payments made for prior period sales | (29,594) | (16,722)
Ending balance | 54,524 | 28,837
Product Returns |  |
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 1,887 | 859
Provision related to current period sales | 812 | 1,496
Credits/payments made for current period sales |  | (391)
Credits/payments made for prior period sales | (69) | (24)
Ending balance | 2,630 | 1,940
Other Incentives |  |
Valuation and Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 2,107 | 1,681
Provision related to current period sales | 14,636 | 10,796
Provision related to prior period sales | (69) | (82)
Credits/payments made for current period sales | (15,038) | (8,834)
Credits/payments made for prior period sales | (2,297) | (1,770)
Ending balance | $ (661) | $ 1,791

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