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Co-Promotion Agreement - Additional Information (Detail) - USD ($)
$ in Thousands
 9 Months Ended 12 Months Ended
Sep. 30, 2018
Dec. 31, 2018
Dec. 31, 2017
Co Promotion Agreement [Line Items]      
Accrued expenses and other current liabilities $ 93,899   $ 58,902
Co-Promotion Agreement (the Agreement)      
Co Promotion Agreement [Line Items]      
Promotion fee as a percentage of gross margin     18.00%
Promotion fee as a percentage gross margin amended, approximately eighteen percent (18%) in 2017, partially offset by certain other refinements    
Maximum co-promotion tail payments receive period 3 years    
Accrued co- promotion tail payments $ 10,800   $ 0
Co-Promotion Agreement (the Agreement) | Scenario Forecast      
Co Promotion Agreement [Line Items]      
Promotion fee as a percentage of gross margin   18.50%  
Co-Promotion Agreement (the Agreement) | Kowa Pharmaceuticals America      
Co Promotion Agreement [Line Items]      
Agreement amended date Jul. 25, 2017    
Accrued expenses and other current liabilities $ 18,000   $ 8,300