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Difference between Benefit from Income Taxes and Amount Computed by Applying Statutory Income Tax Rate to Income Before Taxes (Detail) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Income Tax Disclosure [Abstract] |  |  |
Benefits from taxes at statutory rate | $ (29,087) | $ (13,698) | $ (19,039)
Rate differential | 9,796 | 3,071 | 4,667
Change in valuation reserves | 8,728 | 22,115 | 13,276
Derivative liabilities | 337 |  | (668)
Nondeductible employee compensation | 3,058 | 1,668 | 1,164
Stock option/RSU windfall | (7,684) | (1,182) |
Research and development credits | (1,438) | (1,177) | (1,689)
Tax return to provision adjustments | 6,736 | 5,788 | 4,524
U.S. rate change—tax reform |  | 7,398 |
Cumulative translation adjustment | 5,711 | (12,554) | 7,385
Permanent and other | (404) | 1,635 | (1,573)
Non-deductible interest expense | 267 | (17) | 1,922
Tax reserves | 4,956 |  |
Long-term debt from royalty-bearing instrument | (880) |  |
Provision for income taxes | $ 96 | $ 13,047 | $ 9,969

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