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Nature of Business and Basis of Presentation - Additional Information (Detail) |  | 1 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Jan. 20, 2017 USD ($) | Sep. 30, 2018 Employee | Dec. 31, 2018 USD ($) shares Patient Employee Segment | Dec. 31, 2017 USD ($)
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |
REDUCE-IT study, number of patients enrolled and randomized | Patient |  |  | 8,179 |
Number of operating segments | Segment |  |  | 1 |
Total current assets |  |  | $ 377,997,000 | $ 153,270,000
Cash and cash equivalents |  |  | 249,227,000 | 73,637,000
Accounts receivable, net |  |  | 66,523,000 | 45,318,000
Inventory, net |  |  | 57,802,000 | $ 30,260,000
Other debt outstanding |  |  | $ 0 |
Convertible Debt | 2017 Notes |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |
Convertible senior notes, principal amount | $ 30,000,000 |  |  |
Convertible senior notes, due date | 2047 |  |  |
Convertible senior notes, stated interest rate | 3.50% |  |  |
Convertible senior notes, total ADS into which the debt is exchangeable | shares |  |  | 0 |
Convertible senior notes, repurchase price at option of the issuer | 100.00% |  |  |
Sales Representatives and Managers |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |
Number of sales professionals | Employee |  | 170 | 440 |
Sales Representatives |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |
Number of sales professionals | Employee |  |  | 400 |

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