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Summarize Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017
Valuation And Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | $ 48,093 | $ 27,198
Provision related to current period sales | 258,274 | 178,531
Provision related to prior period sales | (1,914) | (1,075)
Credits/payments made for current period sales | (197,366) | (132,385)
Credits/payments made for prior period sales | (41,843) | (24,176)
Ending balance | 65,244 | 48,093
Trade Allowances |  |
Valuation And Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 12,035 | 3,743
Provision related to current period sales | 46,002 | 35,067
Provision related to prior period sales |  | (323)
Credits/payments made for current period sales | (29,202) | (23,087)
Credits/payments made for prior period sales | (9,340) | (3,365)
Ending balance | 19,495 | 12,035
Rebates, Chargebacks and Discounts |  |
Valuation And Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 32,064 | 20,915
Provision related to current period sales | 190,329 | 126,903
Provision related to prior period sales | (1,845) | (682)
Credits/payments made for current period sales | (148,857) | (96,181)
Credits/payments made for prior period sales | (30,057) | (18,891)
Ending balance | 41,634 | 32,064
Product Returns |  |
Valuation And Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 1,887 | 859
Provision related to current period sales | 1,211 | 1,480
Credits/payments made for current period sales |  | (344)
Credits/payments made for prior period sales | (150) | (108)
Ending balance | 2,948 | 1,887
Other Incentives |  |
Valuation And Qualifying Accounts Disclosure [Line Items] |  |
Beginning balance | 2,107 | 1,681
Provision related to current period sales | 20,732 | 15,081
Provision related to prior period sales | (69) | (70)
Credits/payments made for current period sales | (19,307) | (12,773)
Credits/payments made for prior period sales | (2,296) | (1,812)
Ending balance | $ 1,167 | $ 2,107

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