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Co-Promotion Agreement - Additional Information (Detail) - USD ($) | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017
Co Promotion Agreement [Line Items] |  |
Accrued co- promotion tail payments | $ 17,800,000 |
Accrued expenses and other current liabilities | $ 84,171,000 | $ 58,902,000
Co-Promotion Agreement (the Agreement) |  |
Co Promotion Agreement [Line Items] |  |
Promotion fee as a percentage of gross margin | 18.50% | 18.00%
Promotion fee as a percentage gross margin | amended, approximately eighteen percent (18%) in 2017, partially offset by certain other refinements |
Maximum co-promotion tail payments receive period | 3 years |
Accrued co- promotion tail payments | $ 16,600,000 | $ 0
Co-Promotion Agreement (the Agreement) | Kowa Pharmaceuticals America |  |
Co Promotion Agreement [Line Items] |  |
Agreement amended date | Jul. 25, 2017 |
Accrued expenses and other liabilities | $ 27,600,000 | 8,300,000
Accrued expenses and other current liabilities | $ 18,100,000 | $ 8,300,000

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