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Debt - Long-Term Debt from Royalty-Bearing Instrument-December 2012 Financing - Additional Information (Detail) - USD ($)		1 Months Ended	12 Months Ended
	Dec. 06, 2012	Feb. 27, 2019	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Debt Disclosure [Line Items]
Gain (loss) on change in fair value of derivative liabilities					$ 8,170,000
Long-term debt from royalty-bearing instrument, carrying amount net of unamortized discount			$ 79,710,000	$ 92,403,000
Interest expense, non-cash			2,183,000	2,332,000	$ 7,783,000
CPPIB
Debt Disclosure [Line Items]
Maximum repayment of future revenue and receivables			88,600,000
Repayment under agreement			$ 20,500,000
CPPIB | Subsequent Event
Debt Disclosure [Line Items]
Repayment under agreement		$ 7,700,000
CPPIB | Vascepa
Debt Disclosure [Line Items]
Debt and future repayments percentage of net revenues			10.00%
BioPharma Debt
Debt Disclosure [Line Items]
Amount received at the closing of the agreement	$ 100,000,000
Maximum repayment of future revenue and receivables	150,000,000
Royalty-Bearing Debt
Debt Disclosure [Line Items]
Fair value of embedded derivative liability	$ 14,600,000
Gain (loss) on change in fair value of derivative liabilities			$ 0	0
Long-term debt from royalty-bearing instrument, carrying amount net of unamortized discount			79,700,000	92,400,000
Royalty-Bearing Debt | Cash
Debt Disclosure [Line Items]
Interest expense, contractual coupon interest			5,600,000	6,400,000
Royalty-Bearing Debt | Non Cash
Debt Disclosure [Line Items]
Interest expense, non-cash			$ 2,000,000	$ 2,100,000

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Debt and future repayments net revenues percentage.

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Amount of amortization expense attributable to debt discount (premium) and debt issuance costs.

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Fair value as of the balance sheet date of the embedded derivative or group of embedded derivatives classified as a liability.

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Represents the portion of interest incurred in the period on debt arrangements that was charged against earnings, excluding amortization of debt discount (premium) and financing costs.

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Amount, after unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.

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The net change in the difference between the fair value and the carrying value, or in the comparative fair values, of derivative instruments, including options, swaps, futures, and forward contracts, held at each balance sheet date, that was included in earnings for the period.

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