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Co-Promotion Agreement - Additional Information (Detail) - USD ($)
 12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Co Promotion Agreement [Line Items]    
Accrued co- promotion tail payments $ 17,800,000  
Accrued expenses and other current liabilities $ 84,171,000 $ 58,902,000
Co-Promotion Agreement (the Agreement)    
Co Promotion Agreement [Line Items]    
Promotion fee as a percentage of gross margin 18.50% 18.00%
Promotion fee as a percentage gross margin amended, approximately eighteen percent (18%) in 2017, partially offset by certain other refinements  
Maximum co-promotion tail payments receive period 3 years  
Accrued co- promotion tail payments $ 16,600,000 $ 0
Co-Promotion Agreement (the Agreement) | Kowa Pharmaceuticals America    
Co Promotion Agreement [Line Items]    
Agreement amended date Jul. 25, 2017  
Accrued expenses and other liabilities $ 27,600,000 8,300,000
Accrued expenses and other current liabilities $ 18,100,000 $ 8,300,000