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Development, Commercialization and Supply Agreement - Additional Information1 (Detail) - Out-licenses - Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date: 2019-01-01
Dec. 31, 2018
Eddingpharm  
License And Collaboration Agreements [Line Items]  
Revenue recognized over remaining period 16 years
HLS  
License And Collaboration Agreements [Line Items]  
Revenue recognized over remaining period 12 years