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Co-Promotion Agreement - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended	6 Months Ended	12 Months Ended
	Jun. 30, 2019	Jun. 30, 2019	Dec. 31, 2018
Co Promotion Agreement [Line Items]
Accrued expenses and other current liabilities	$ 103,495	$ 103,495	$ 84,171
Co-Promotion Agreement \| Kowa Pharmaceuticals America, Inc.
Co Promotion Agreement [Line Items]
Agreement amended date		Jul. 25, 2017
Promotion fee as a percentage of gross margin			18.50%
Maximum co-promotion tail payments receive period		3 years
Co-promotion tail payments receivable			$ 17,800
Tail payments during the period	2,400
Accrued co- promotion tail payments	14,600	$ 14,600	$ 16,600
Accrued expenses and other current liabilities	$ 8,500	$ 8,500