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Condensed Consolidated Statement of Changes in Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Total
Preferred Shares
Common Shares
Treasury Stock
Additional Paid-in Capital
Accumulated Deficit
Balance at Dec. 31, 2017 $ (65,100) $ 24,364 $ 208,768 $ (4,229) $ 977,866 $ (1,271,869)
Balance (in shares) at Dec. 31, 2017   328,184,640 272,719,044 (1,697,033)    
Balance (Cumulative-effect adjustment) | Accounting Standards Update 2014-09 (218)         (218)
Balance at Jan. 01, 2018 (65,318) $ 24,364 $ 208,768 $ (4,229) 977,866 (1,272,087)
Balance (in shares) at Jan. 01, 2018   328,184,640 272,719,044 (1,697,033)    
Balance at Dec. 31, 2017 (65,100) $ 24,364 $ 208,768 $ (4,229) 977,866 (1,271,869)
Balance (in shares) at Dec. 31, 2017   328,184,640 272,719,044 (1,697,033)    
Issuance of common stock, net of transaction costs 70,007   $ 14,635   55,372  
Issuance of common stock, net of transaction costs (shares)     20,616,438      
Exercise of stock options 1,548   $ 541   1,007  
Exercise of stock options (in shares)     782,553      
Vesting of restricted stock units (2,553)   $ 1,302 $ (2,553) (1,302)  
Vesting of restricted stock units (in shares)     1,838,380 (675,242)    
Stock-based compensation 3,754       3,754  
Loss for the period (24,095)         (24,095)
Balance at Mar. 31, 2018 (16,657) $ 24,364 $ 225,246 $ (6,782) 1,036,697 (1,296,182)
Balance (in shares) at Mar. 31, 2018   328,184,640 295,956,415 (2,372,275)    
Balance at Dec. 31, 2017 $ (65,100) $ 24,364 $ 208,768 $ (4,229) 977,866 (1,271,869)
Balance (in shares) at Dec. 31, 2017   328,184,640 272,719,044 (1,697,033)    
Exercise of stock options (in shares) 956,232          
Loss for the period $ (58,305)          
Balance at Jun. 30, 2018 (46,687) $ 24,364 $ 225,507 $ (6,909) 1,040,743 (1,330,392)
Balance (in shares) at Jun. 30, 2018   328,184,640 296,348,903 (2,413,527)    
Balance at Mar. 31, 2018 (16,657) $ 24,364 $ 225,246 $ (6,782) 1,036,697 (1,296,182)
Balance (in shares) at Mar. 31, 2018   328,184,640 295,956,415 (2,372,275)    
Issuance of common stock under employee stock purchase plan 423   $ 85   338  
Issuance of common stock under employee stock purchase plan (in shares)     127,872      
Exercise of stock options 278   $ 116   162  
Exercise of stock options (in shares)     173,679      
Vesting of restricted stock units (127)   $ 60 $ (127) (60)  
Vesting of restricted stock units (in shares)     90,937 (41,252)    
Stock-based compensation 3,606       3,606  
Loss for the period (34,210)         (34,210)
Balance at Jun. 30, 2018 (46,687) $ 24,364 $ 225,507 $ (6,909) 1,040,743 (1,330,392)
Balance (in shares) at Jun. 30, 2018   328,184,640 296,348,903 (2,413,527)    
Balance at Dec. 31, 2018 152,330 $ 21,850 $ 246,663 $ (10,413) 1,282,762 (1,388,532)
Balance (in shares) at Dec. 31, 2018   289,317,460 329,110,863 (3,260,850)    
Exercise of stock options 15,456   $ 2,496   12,960  
Exercise of stock options (in shares)     3,838,739      
Vesting of restricted stock units (9,080)   $ 929 $ (9,080) (929)  
Vesting of restricted stock units (in shares)     1,416,124 (526,708)    
Stock-based compensation 6,596       6,596  
Loss for the period (24,431)         (24,431)
Balance at Mar. 31, 2019 140,871 $ 21,850 $ 250,088 $ (19,493) 1,301,389 (1,412,963)
Balance (in shares) at Mar. 31, 2019   289,317,460 334,365,726 (3,787,558)    
Balance at Dec. 31, 2018 $ 152,330 $ 21,850 $ 246,663 $ (10,413) 1,282,762 (1,388,532)
Balance (in shares) at Dec. 31, 2018   289,317,460 329,110,863 (3,260,850)    
Exercise of stock options (in shares) 4,458,143          
Loss for the period $ (26,251)          
Balance at Jun. 30, 2019 149,087 $ 21,850 $ 250,588 $ (20,533) 1,311,965 (1,414,783)
Balance (in shares) at Jun. 30, 2019   289,317,460 335,149,425 (3,841,615)    
Balance at Mar. 31, 2019 140,871 $ 21,850 $ 250,088 $ (19,493) 1,301,389 (1,412,963)
Balance (in shares) at Mar. 31, 2019   289,317,460 334,365,726 (3,787,558)    
Issuance of common stock under employee stock purchase plan 837   $ 30   807  
Issuance of common stock under employee stock purchase plan (in shares)     47,358      
Exercise of stock options 1,888   $ 396   1,492  
Exercise of stock options (in shares)     619,404      
Vesting of restricted stock units (1,040)   $ 74 $ (1,040) (74)  
Vesting of restricted stock units (in shares)     116,937 (54,057)    
Stock-based compensation 8,351       8,351  
Loss for the period (1,820)         (1,820)
Balance at Jun. 30, 2019 $ 149,087 $ 21,850 $ 250,588 $ (20,533) $ 1,311,965 $ (1,414,783)
Balance (in shares) at Jun. 30, 2019   289,317,460 335,149,425 (3,841,615)