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Stock Incentive Plans and Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2019

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Stock Option Activity

The following table summarizes all stock option activity for the year ended December 31, 2019

In thousands (except per share amounts and years)		Number of Shares				Weighted Average Exercise Price				Weighted Average Remaining Contractual Term		Aggregate Intrinsic Value
Outstanding as of January 1, 2019			19,263			$	4.29
Granted			2,648				17.07
Forfeited			(291	)			10.31
Expired			(3	)			4.04
Exercised			(5,998	)			4.09
Outstanding as of December 31, 2019			15,619				6.43			6.5 years		$	234,499
Exercisable as of December 31, 2019			10,310				3.75			5.4 years			182,417
Vested and expected to vest as of December 31, 2019			15,354			$	6.34			6.4 years		$	231,895
Available for future grant as of December 31, 2019			7,851

Assumptions Used to Estimate Fair Value of Share-Based Payment Awards

For 2019, 2018, and 2017, the Company used the following assumptions to estimate the fair value of share-based payment awards:

		2019			2018			2017
Risk-free interest rate		1.55% - 2.95%			2.18% - 3.00%			1.77% - 2.01%
Expected dividend yield		0.00%			0.00%			0.00%
Expected option life (years)		6.25			6.25			6.25
Expected volatility		92% - 94%			71% - 92%			73% - 82%

Restricted Stock Unit Activity

The following table presents the restricted stock unit activity for the years ended December 31, 2019 and 2018:

In thousands (except per share amounts)		Shares				Weighted Average Grant Date Fair Value
Outstanding as of January 1, 2018			12,006			$	2.50
Granted			2,633				4.32
Vested			(4,611	)			2.20
Forfeited			(395	)			3.43
Outstanding as of December 31, 2018			9,633				3.12
Granted			1,473				16.83
Vested			(3,970	)			2.56
Forfeited			(215	)			3.25
Outstanding as of December 31, 2019			6,921			$	6.34

Stock-Based Compensation Expense Related to Option Awards

The following table presents the stock-based compensation expense related to stock-based awards for the years ended December 31, 2019, 2018, and 2017:

In thousands		2019				2018				2017
Research and development		$	4,615			$	2,898			$	2,122
Selling, general and administrative			26,302				15,908				11,838
Stock-based compensation expense		$	30,917			$	18,806			$	13,960

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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