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Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Total revenue, net $ 429,755 $ 229,214 $ 181,104
Less: Cost of goods sold 96,019 54,543 44,952
Gross margin 333,736 174,671 136,152
Operating expenses:      
Selling, general and administrative 323,623 226,996 134,549
Research and development 34,392 55,900 47,158
Total operating expenses 358,015 282,896 181,707
Operating loss (24,279) (108,225) (45,555)
Interest expense (6,626) (8,872) (9,766)
Interest income 8,499 1,074 429
Other (expense) income, net (75) (326) 74
Loss from operations before taxes (22,481) (116,349) (54,818)
Provision for income taxes (164) (96) (13,047)
Net loss $ (22,645) $ (116,445) $ (67,865)
Loss per share:      
Basic $ (0.07) $ (0.39) $ (0.25)
Diluted $ (0.07) $ (0.39) $ (0.25)
Weighted average shares outstanding:      
Basic 342,538 297,237 270,652
Diluted 342,538 297,237 270,652
Product Revenue, Net      
Total revenue, net $ 427,391 $ 228,371 $ 179,825
Licensing Revenue      
Total revenue, net $ 2,364 $ 843 $ 1,279