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Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2020
Accounting Policies [Abstract] |
Summary of Impact of Accounts Receivable Reserves on Gross Trade Accounts Receivable Balances | The following table summarizes the impact of accounts receivable reserves on the gross trade accounts receivable balances at December 31, 2020 and 2019:
In thousands |  | December 31, 2020 |  |  | December 31, 2019 |
Gross trade accounts receivable |  | $ | 203,875 |  |  | $ | 149,567 |
Trade allowances |  |  | (36,242 | ) |  |  | (29,261 | )
Chargebacks |  | $ | (12,114 | ) |  |  | (3,876 | )
Allowance for doubtful accounts |  |  | (945 | ) |  |  | — |
Accounts receivable, net |  | $ | 154,574 |  |  | $ | 116,430 |
Calculation of Net Loss and Number of Shares Used to Compute Basic and Diluted Net Loss per Share | The calculation of net loss and the number of shares used to compute basic and diluted net loss per share for the years ended December 31, 2020, 2019, and 2018 are as follows:
In thousands |  | 2020 |  |  | 2019 |  |  | 2018 |
Net loss—basic and diluted |  | $ | (18,000 | ) |  | $ | (22,645 | ) |  | $ | (116,445 | )
Weighted average shares outstanding—basic and diluted |  |  | 381,759 |  |  |  | 342,538 |  |  |  | 297,237 |
Net loss per share—basic and diluted |  | $ | (0.05 | ) |  | $ | (0.07 | ) |  | $ | (0.39 | )
Anti-Dilutive Securities Not Included in the Computation of Net Loss or Earnings per Share | For the years ended December 31, 2020, 2019 and 2018, the following potentially dilutive securities were not included in the computation of net loss per share because the effect would be anti-dilutive:
In thousands |  | 2020 |  |  | 2019 |  |  | 2018 |
Stock options |  |  | 16,664 |  |  |  | 15,619 |  |  |  | 19,263 |
Restricted stock and restricted stock units |  |  | 7,710 |  |  |  | 6,921 |  |  |  | 9,633 |
Preferred stock (if converted) |  |  | — |  |  |  | 28,932 |  |  |  | 28,932 |
Estimated Fair Value of Assets and Liability | The following tables present information about the estimated fair value of the Company’s assets and liabilities as of December 31, 2020 and 2019 and indicate the fair value hierarchy of the valuation techniques the Company utilized to determine such fair value:
|  | December 31, 2020 |
In thousands |  | Total |  |  | Level 1 |  |  | Level 2 |  |  | Level 3 |
Asset: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Money Market Fund |  | $ | 88,266 |  |  | $ | 88,266 |  |  | $ | — |  |  | $ | — |
U.S. Treasury Shares |  |  | 48,356 |  |  |  | 48,356 |  |  |  | — |  |  |  | — |
Corporate Bonds |  |  | 179,864 |  |  |  | — |  |  |  | 179,864 |  |  |  | — |
Commercial Paper |  |  | 106,650 |  |  |  | — |  |  |  | 106,650 |  |  |  | — |
Agency Securities |  |  | 20,782 |  |  |  | — |  |  |  | 20,782 |  |  |  | — |
Repo Securities |  |  | 10,000 |  |  |  | — |  |  |  | 10,000 |  |  |  | — |
Asset Backed Securities |  |  | 8,599 |  |  |  | — |  |  |  | 8,599 |  |  |  | — |
Certificate of Deposit |  |  | 6,125 |  |  |  | — |  |  |  | 6,125 |  |  |  | — |
Non-US Government |  |  | 5,240 |  |  |  | — |  |  |  | 5,240 |  |  |  | — |
Total |  | $ | 473,882 |  |  | $ | 136,622 |  |  | $ | 337,260 |  |  | $ | — |
|  | December 31, 2019 |
In thousands |  | Total |  |  | Level 1 |  |  | Level 2 |  |  | Level 3 |
Asset: |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Money Market Fund |  | $ | 10,078 |  |  | $ | 10,078 |  |  | $ | — |  |  | $ | — |
Carrying Amounts and Estimated Fair Values of Debt from Royalty-Bearing Instrument | The carrying amounts of accounts payable and accrued liabilities approximate fair value because of their short-term nature. The carrying amounts and the estimated fair values of the debt from royalty-bearing instrument as of December 31, 2020 and 2019 are as follows:
|  | December 31, 2020 |  |  | December 31, 2019 |
In thousands |  | Carrying Value |  |  | Estimated Fair Value |  |  | Carrying Value |  |  | Estimated Fair Value |
Debt from royalty-bearing instrument |  | $ | — |  |  | $ | — |  |  | $ | 49,702 |  |  | $ | 50,400 |

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