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Revenue Recognition - Summarize Activity of the Net Product Revenue Allowance and Reserve Categories (Detail) - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Valuation And Qualifying Accounts Disclosure [Line Items]    
Beginning balance $ 190,827 $ 128,557
Provision related to current period sales 627,571 585,206
Provision related to prior period sales (854) (3,872)
Credits/payments made for current period sales (362,460) (384,035)
Credits/payments made for prior period sales (172,378) (118,742)
Ending balance 282,706 207,114
Trade Allowances    
Valuation And Qualifying Accounts Disclosure [Line Items]    
Beginning balance 36,242 29,261
Provision related to current period sales 90,761 95,239
Credits/payments made for current period sales (27,635) (32,364)
Credits/payments made for prior period sales (34,511) (29,067)
Ending balance 64,857 63,069
Rebates, Chargebacks and Discounts    
Valuation And Qualifying Accounts Disclosure [Line Items]    
Beginning balance 141,201 90,997
Provision related to current period sales 497,726 437,030
Provision related to prior period sales (854) (3,872)
Credits/payments made for current period sales (303,029) (304,903)
Credits/payments made for prior period sales (131,320) (85,731)
Ending balance 203,724 133,521
Product Returns    
Valuation And Qualifying Accounts Disclosure [Line Items]    
Beginning balance 7,797 4,579
Provision related to current period sales 2,647 2,534
Credits/payments made for prior period sales (958) (223)
Ending balance 9,486 6,890
Other Incentives    
Valuation And Qualifying Accounts Disclosure [Line Items]    
Beginning balance 5,587 3,720
Provision related to current period sales 36,437 50,403
Credits/payments made for current period sales (31,796) (46,768)
Credits/payments made for prior period sales (5,589) (3,721)
Ending balance $ 4,639 $ 3,634