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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (6,969) $ (22,926)
Adjustments to reconcile loss to net cash (used in) provided by operating activities:    
Depreciation and amortization 443 446
Amortization of investments 1,564 771
Stock-based compensation 26,836 34,305
Amortization of debt discount and debt issuance costs   601
Amortization of intangible asset 1,633 1,081
Changes in assets and liabilities:    
Accounts receivable, net 5,213 (30,862)
Inventory (120,404) (71,762)
Prepaid and other current assets 9,601 (13,023)
Other long-term assets (24)  
Interest receivable 723 (1,732)
Accrued interest payable   (348)
Deferred revenue (1,500) (1,941)
Accounts payable and other current liabilities 45,582 121,240
Other long-term liabilities (995) 727
Net cash (used in) provided by operating activities (38,297) 16,577
CASH FLOWS FROM INVESTING ACTIVITIES:    
Sale and maturities of securities 312,150 186,714
Purchases of securities (233,067) (587,111)
Disposal (purchase) of furniture, fixtures and equipment 4 (252)
Net cash provided by (used in) investing activities 79,087 (400,649)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from issuance of common stock, net of transaction costs 1,028 848
Proceeds from exercise of stock options, net of transaction costs 2,615 1,861
Payment of transaction costs for conversion of preferred stock   (266)
Payment on debt from royalty-bearing instrument   (40,916)
Taxes paid related to stock-based awards (8,520) (14,828)
Net cash used in financing activities (4,877) (53,301)
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH 35,913 (437,373)
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD 190,879 648,495
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD 226,792 211,122
Cash Received Paid During Period For [Abstract]    
Interest   (1,882)
Income taxes 3,670 $ (197)
Supplemental disclosure of non-cash transactions:    
Laxdale Milestone $ 12,000