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Commitments and Contingencies - Additional Information (Detail) $ in Millions | Sep. 30, 2022 USD ($) | Sep. 30, 2022 GBP (£) | Jul. 13, 2022 GBP (£) | Mar. 26, 2021 GBP (£)
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Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Future contractual purchase obligations without consideration | $ | $ 81.5 |  |  |
Further Indication for AMR101 | Marketing Approval In Europe |  |  |  |
Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Potential aggregate stock or cash payment |  |  |  | £ 7,500,000
Aggregate stock or cash payment upon potential market approval |  |  | £ 7,500,000 |
Further Indication for AMR101 | Potential Marketing Approval 1 |  |  |  |
Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Aggregate stock or cash payment upon potential market approval | 5.5 | £ 5,000,000 |  |
Further Indication for AMR101 | Potential Marketing Approval 2 |  |  |  |
Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Aggregate stock or cash payment upon potential market approval | $ 5.5 | £ 5,000,000 |  |

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