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Income Taxes - Income Taxes Effect of Each Type of Temporary Difference Comprising Net Differed Tax Asset (Detail) - USD ($) $ in Thousands | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
--- | --- | --- | ---
Deferred tax assets: |  |  |
Net operating losses | $ 136,862 | $ 127,378 |
Stock-based compensation | 11,616 | 8,563 |
Tax credits | 2,639 | 15,803 |
Capitalized R&D | 4,723 |  |
Lease liability | 2,583 | 2,348 |
Other reserves and accrued liabilities | 11,895 | 11,257 |
Gross deferred tax assets | 170,318 | 165,349 |
Less: valuation allowance | (165,378) | (160,295) | $ (160,841)
Total deferred tax assets | 4,940 | 5,054 |
Deferred tax liabilities: |  |  |
Depreciation and amortization | (3,337) | (3,404) |
Lease asset | (1,603) | (1,639) |
Other liabilities | 0 | (11) |
Total deferred tax liabilities | (4,940) | (5,054) |
Net deferred tax assets | $ 0 | $ 0 |

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