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Equity - Incentive Equity Awards - Summary of Equity Awards Activity (Detail) - USD ($)
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Stockholders Equity Note [Line Items]    
Stock Options Issued 33,303 1,203,845
Gross Proceeds $ 59,686 $ 2,921,000
Restricted Stock Units (RSUs)    
Stockholders Equity Note [Line Items]    
Common Shares Issued in settlement of RSUs and Performance Based RSUs Vested 1,940,371 1,203,845
Shares retained for settlement of employee tax obligations 500,064 782,917
Performance-Based RSUs    
Stockholders Equity Note [Line Items]    
Common Shares Issued in settlement of RSUs and Performance Based RSUs Vested [1]   1,923,316
Shares retained for settlement of employee tax obligations   816,931
[1] Performance-based RSUs vested in connection with the achievement of certain regulatory and sales performance conditions associated with the REDUCE-IT clinical trial and subsequent revenue growth. These performance-based RSUs have fully vested as of August 2021.