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Development, Commercialization and Supply Agreement - Additional Information (Detail) | 1 Months Ended | 12 Months Ended
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Oct. 31, 2023 USD ($) | Jul. 31, 2023 USD ($) | Jun. 30, 2023 USD ($) | Feb. 28, 2023 USD ($) | Jan. 31, 2023 USD ($) | Jan. 31, 2022 USD ($) | Jan. 31, 2021 USD ($) | Feb. 29, 2020 USD ($) | Jan. 31, 2020 USD ($) | Sep. 30, 2018 USD ($) | Sep. 30, 2017 USD ($) | Mar. 31, 2016 USD ($) | Feb. 28, 2015 USD ($) | Dec. 31, 2023 USD ($) Item | Dec. 31, 2022 USD ($) | Dec. 31, 2021 USD ($) | Dec. 31, 2018 USD ($)
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognized related to upfront and milestone payments |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,369,000 |  |
Revenue recognized related to upfront and milestone payments |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 18,586,000 |  |  |
Licenses revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | 306,911,000 | 369,193,000 | $ 583,187,000 |
Deferred revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | 4,850,000 | 15,346,000 | 16,709,000 |
Product Revenue, Net |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licenses revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 285,299,000 | 366,511,000 | $ 580,320,000 |
Mochida Pharmaceutical Co., Ltd. | In-licenses |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Milestones payment |  |  |  |  | $ 1,000,000 | $ 1,000,000 | $ 1,000,000 |  |  |  |  |  |  |  |  |  |
Mochida Pharmaceutical Co., Ltd. | In-licenses | Research and Development Expense |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront payment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 2,700,000
Edding | Out-licenses |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable up-front received |  |  |  |  |  |  |  |  |  |  |  |  | $ 15,000,000 |  |  |  |
Number of indications of the regulatory milestone events relating to the submission and approval | Item |  |  |  |  |  |  |  |  |  |  |  |  |  | 3 |  |  |
Amounts to be received upon achievement of the regulatory milestone events |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 25,000,000 |  |  |
Sales-based milestone event payment |  |  |  |  |  |  |  |  |  |  |  |  |  | 120,000,000 |  |  |
Milestone payments received |  |  |  |  |  |  |  |  |  |  |  |  |  | 9,000,000 |  |  |
Revenue recognized related to upfront and milestone payments |  |  |  |  |  |  |  |  |  |  |  |  |  | 12,900,000 | 600,000 |  |
Deferred revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | 4,400,000 | 9,300,000 |  |
Edding | Out-licenses | Licensing Revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licenses revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | 20,600,000 | 7,700,000 |  |
Edding | Out-licenses | Product Revenue, Net |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licenses revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,800,000 | 200,000 |  |
Edding | Out-licenses | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Additional upfront payment eligible to receive based on development, regulatory and sales Milestone |  |  |  |  |  |  |  |  |  |  |  |  |  | 145,000,000 |  |  |
Amounts to be received upon achievement of the regulatory milestone events |  |  |  |  |  |  |  |  |  |  |  |  |  | 15,000,000 |  |  |
Sales-based milestone event payment |  |  |  |  |  |  |  |  |  |  |  |  |  | 50,000,000 |  |  |
Edding | Out-licenses | Minimum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amounts to be received upon achievement of the regulatory milestone events |  |  |  |  |  |  |  |  |  |  |  |  |  | 2,000,000 |  |  |
Sales-based milestone event payment |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,000,000 |  |  |
Edding | Out-licenses | Clinical Trial Application |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable milestone payment received |  |  |  |  |  |  |  |  |  |  |  | $ 1,000,000 |  |  |  |  |
Edding | Out-licenses | Achievement of REDUCE-IT Trial |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable milestone payment received | $ 3,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Edding | Out-licenses | MARINE |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Additional upfront payment eligible to receive based on development, regulatory and sales Milestone |  |  |  |  |  |  |  |  |  |  |  |  |  | 3,900,000 |  |  |
Additional license revenues |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,000,000 |  |  |
Reduction in net loss |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,000,000 |  |  |
Remaining performance period amount |  |  |  |  |  |  |  |  |  |  |  |  |  | 1,100,000 |  |  |
Edding | Out-licenses | MARINE | VASCEPA |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable milestone payment received |  |  | $ 5,000,000 |  |  |  |  |  |  |  |  |  |  | $ 5,000,000 |  |  |
Edding | Out-licenses | MARINE | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognition period of non-refundable up-front payment |  |  |  |  |  |  |  |  |  |  |  |  |  | 3 years |  |  |
Edding | Out-licenses | MARINE | Minimum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognition period of non-refundable up-front payment |  |  |  |  |  |  |  |  |  |  |  |  |  | 11 years |  |  |
Biologix FZCo |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognition period of non-refundable up-front payment |  |  |  |  |  |  |  |  |  |  |  |  |  | 8 years |  |  |
Biologix FZCo | Out-licenses |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable milestone payment received |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 5,300,000 |  |  |
Reduction in net loss |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,300,000 |  |  |
Revenue recognition period of non-refundable up-front payment |  |  |  |  |  |  |  |  |  |  |  | 10 years |  |  |  |  |
Biologix FZCo | Out-licenses | Product Revenue, Net |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licenses revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | 3,400,000 | 1,000,000 |  |
HLS | Out-licenses |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable up-front received |  |  |  |  |  |  |  |  |  |  | $ 5,000,000 |  |  |  |  |  |
Non-refundable milestone payment received |  |  |  |  |  |  |  | $ 2,500,000 | $ 3,800,000 | $ 2,500,000 |  |  |  |  |  |  |
Revenue recognized related to upfront and milestone payments |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,600,000 | 700,000 |  |
Non-refundable milestone payment received |  |  |  |  |  |  |  |  |  |  | $ 3,800,000 |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 5,600,000 |  |
Non-refundable up-front received period |  |  |  |  |  |  |  |  |  |  | 6 months |  |  |  |  |  |
HLS | Out-licenses | Health Canada |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable milestone payment received |  |  |  |  |  |  |  |  |  |  | $ 2,500,000 |  |  |  |  |  |
HLS | Out-licenses | Licensing Revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licenses revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | 13,700,000 | 8,200,000 |  |
HLS | Out-licenses | Product Revenue, Net |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licenses revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | 3,100,000 | $ 2,900,000 |  |
HLS | Out-licenses | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Additional upfront payment eligible to receive based on development, regulatory and sales Milestone |  |  |  |  |  |  |  |  |  |  | 50,000,000 |  |  |  |  |  |
HLS | Out-licenses | Achievement of REDUCE-IT Trial |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable milestone payment received |  |  |  |  |  |  |  |  |  |  | $ 2,500,000 |  |  |  |  |  |
CSL Seqirus | Out-licenses |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable up-front received |  |  |  | $ 500,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Licenses revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | 500,000 |  |  |
Upfront payment receivable |  |  |  | 500,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Event-related milestone payments receivable |  |  |  | 8,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Additional product-related milestone payments receivable |  |  |  | $ 4,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |
Lotus Pharmaceuticals | VAZKEPA |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Non-refundable up-front received |  | $ 300,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront payment receivable |  | $ 300,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Lotus Pharmaceuticals | Out-licenses |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
License And Collaboration Agreements [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Licenses revenue |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 300,000 |  |  |

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