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Commitments and Contingencies - Additional Information (Detail) $ in Millions | Dec. 31, 2023 USD ($) | Dec. 31, 2023 GBP (£) | Jul. 13, 2022 GBP (£) | Mar. 26, 2021 GBP (£)
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Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Future contractual purchase obligations without consideration | $ 37.0 |  |  |
Accured estimated liability | 8.0 |  |  |
Additional estimated liability | 7.8 |  |  |
Minimum |  |  |  |
Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Estimated liability | 8.0 |  |  |
Maximum |  |  |  |
Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Estimated liability | 15.8 |  |  |
Regulatory Approval in Europe |  |  |  |
Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Additional future contractual purchase obligations without consideration | 186.5 |  |  |
Further Indication for AMR101 | Marketing Approval In Europe |  |  |  |
Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Potential aggregate stock or cash payment | £ |  |  |  | £ 7,500,000
Aggregate stock or cash payment upon potential market approval | £ |  |  | £ 7,500,000 |
Further Indication for AMR101 | Potential Marketing Approval 1 |  |  |  |
Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Aggregate stock or cash payment upon potential market approval | 6.4 | £ 5,000,000 |  |
Further Indication for AMR101 | Potential Marketing Approval 2 |  |  |  |
Commitments And Contingencies Disclosure [Line Items] |  |  |  |
Aggregate stock or cash payment upon potential market approval | $ 6.4 | £ 5,000,000 |  |

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- Definition Amount of the recorded obligation to transfer funds in the future for fixed or minimum amounts or quantities of goods or services at fixed or minimum prices (for example, as in take-or-pay contracts or throughput contracts). + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 440 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 6 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482648/440-10-50-6 + Details
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