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Stock Incentive Plans and Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2023

Share-Based Payment Arrangement [Abstract]

Stock Option Activity

The following table summarizes all stock option activity for the year ended December 31, 2023:

In thousands (except per share amounts and years)		Number of Shares				Weighted Average Exercise Price				Weighted Average Remaining Contractual Term		Aggregate Intrinsic Value
Outstanding as of January 1, 2023			19,182			$	5.80
Granted			18,363				1.27
Forfeited			(8,221	)			4.85
Expired			(128	)			7.54
Exercised			(1,240	)			1.50
Outstanding as of December 31, 2023			27,956				3.21			7.3 years		$	131
Exercisable as of December 31, 2023			12,333				5.72			4.4 years		$	-
Vested and expected to vest as of December 31, 2023			27,114				3.35			6.6 years		$	113
Available for future grant as of December 31, 2023			22,984

Assumptions Used to Estimate Fair Value of Share-Based Payment Awards

For 2023, 2022, and 2021, the Company used the following assumptions to estimate the fair value of share-based payment awards under the Black-Scholes model:

		2023		2022		2021
Risk-free interest rate		3.59% - 4.72%		1.64% - 4.35%		0.53% - 1.36%
Expected dividend yield		0.00%		0.00%		0.00%
Expected option life (years)		6.25		6.25		6.25
Expected volatility		101% - 104%		96% - 101%		96% - 99%

The Company used the following assumptions to estimate the fair value of share-based payment awards under the Monte Carlo model in 2023:

		2023
Risk-free interest rate		4.06% - 4.09%
Expected dividend yield		0.00%
Expected option life (years)		9
Expected volatility		42.5% - 43.00%

Restricted Stock Unit Activity

The following table presents the restricted stock unit activity for the year ended December 31, 2023:

In thousands (except per share amounts)		Shares				Weighted Average Grant Date Fair Value
Outstanding as of January 1, 2023			14,461				3.98
Granted			11,048				1.73
Vested			(4,249	)			3.91
Forfeited			(9,057	)			2.85
Expired			(220	)			16.87
Outstanding as of December 31, 2023			11,983			$	1.70

Stock-Based Compensation Expense Related to Option Awards

The following table presents the stock-based compensation expense related to stock-based awards for the years ended December 31, 2023, 2022, and 2021:

In thousands		2023				2022				2021
Research and development		$	4,187			$	4,465			$	4,327
Selling, general and administrative			12,493				22,339				32,305
Restructuring			(1,034	)			(591	)			306
Stock-based compensation expense		$	15,646			$	26,213			$	36,938

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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Disclosure of the number and weighted-average grant date fair value for restricted stock and restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock and restricted stock units that were granted, vested, or forfeited during the year.

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