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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (82,183) $ (59,112) $ (105,803)
Adjustments to reconcile net (loss) income to net cash used in operating activities:      
Depreciation and amortization 98 160 551
(Accretion) amortization of investments (5,729) (3,696) 473
Stock-based compensation 17,705 15,646 26,213
Amortization of intangible asset 2,915 2,805 2,545
Changes in assets and liabilities:      
Accounts receivable, net 11,284 (2,573) 32,663
Inventory 105,443 56,121 (36,422)
Prepaid and other current assets (934) 7,874 2,860
Other long-term assets 147 (278) (2)
Interest receivable (70) 248 341
Deferred revenue (4,850) (10,496) (1,363)
Accounts payable, accrued expenses and other current liabilities (76,987) (164) (102,729)
Other long-term liabilities 2,141 345 581
Net cash (used in) provided by operating activities (31,020) 6,880 (180,092)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Maturities of securities 232,800 190,108 257,520
Purchases of securities (278,776) (215,097) (81,633)
Investment in software and website development costs   (509) (599)
Purchases of furniture, fixtures and equipment   (24)  
Net cash (used in) provided by investing activities (45,976) (25,522) 175,288
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from issuance of common stock under employee stock purchase plan 121 330 605
Proceeds from exercise of stock options 10 1,882 60
Taxes related to stock-based awards (1,574) (1,982) (1,044)
Net cash (used in) provided by financing activities (1,443) 230 (379)
NET DECREASE IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH (78,439) (18,412) (5,183)
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD 199,777 218,189 223,372
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD 121,338 199,777 218,189
Cash paid during the year for:      
Income taxes (3,982) (2,367) (1,782)
Supplemental disclosure of non-cash transactions:      
Shares issued in settlement of Laxdale milestone payment     8,203
Initial recognition of operating lease right-of-use asset $ 1,069 607 $ 2,041
Initial recognition of furniture, fixtures and equipment lease   $ 624