<SEC-DOCUMENT>0000899140-25-000466.txt : 20250325
<SEC-HEADER>0000899140-25-000466.hdr.sgml : 20250325
<ACCEPTANCE-DATETIME>20250325203757
ACCESSION NUMBER:		0000899140-25-000466
CONFORMED SUBMISSION TYPE:	SCHEDULE 13D/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250325
DATE AS OF CHANGE:		20250325

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AMARIN CORP PLC\UK
		CENTRAL INDEX KEY:			0000897448
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			X0
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-52399
		FILM NUMBER:		25769802

	BUSINESS ADDRESS:	
		STREET 1:		SPACES SOUTH DOCKLANDS, BLOCK C
		STREET 2:		77 SIR JOHN ROGERSON'S QUAY
		CITY:			DUBLIN 2
		STATE:			L2
		ZIP:			D02 VK60
		BUSINESS PHONE:		353 1 6699 020

	MAIL ADDRESS:	
		STREET 1:		SPACES SOUTH DOCKLANDS, BLOCK C
		STREET 2:		77 SIR JOHN ROGERSON'S QUAY
		CITY:			DUBLIN 2
		STATE:			L2
		ZIP:			D02 VK60

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AMARIN PHARMACEUTICALS PLC
		DATE OF NAME CHANGE:	20000201

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ETHICAL HOLDINGS PLC
		DATE OF NAME CHANGE:	19930322

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Sarissa Capital Management LP
		CENTRAL INDEX KEY:			0001577524
		ORGANIZATION NAME:           	
		EIN:				900924432
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		660 STEAMBOAT ROAD
		CITY:			GREENWICH
		STATE:			CT
		ZIP:			06830
		BUSINESS PHONE:		203-302-2330

	MAIL ADDRESS:	
		STREET 1:		660 STEAMBOAT ROAD
		CITY:			GREENWICH
		STATE:			CT
		ZIP:			06830
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13D/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13D" xmlns:com="http://www.sec.gov/edgar/common">
<headerData>
<submissionType>SCHEDULE 13D/A</submissionType>
<previousAccessionNumber>0000899140-22-000088</previousAccessionNumber>
<filerInfo>
<filer>
<filerCredentials>
<cik>0001577524</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>



</filerInfo>
</headerData>
<formData>
<coverPageHeader>
<amendmentNo>15</amendmentNo>
<securitiesClassTitle>Ordinary Shares, par value 50 pence per share</securitiesClassTitle>
<dateOfEvent>03/25/2025</dateOfEvent>
<previouslyFiledFlag>false</previouslyFiledFlag>
<issuerInfo>
<issuerCIK>0000897448</issuerCIK>
<issuerCUSIP>023111206</issuerCUSIP>
<issuerName>Amarin Corporation PLC/UK</issuerName>
<address>
<com:street1>One Central Plaza, 5th Floor</com:street1>
<com:street2>36 Dame Street</com:street2>
<com:city>Dublin 2</com:city>
<com:stateOrCountry>L2</com:stateOrCountry>
<com:zipCode>D02 EF64</com:zipCode>
</address>
</issuerInfo>
<authorizedPersons>
<notificationInfo>
<personName>Mark DiPaolo</personName>
<personPhoneNum>203-302-2330</personPhoneNum>
<personAddress>
<com:street1>Sarissa Capital Management LP</com:street1>
<com:street2>660 Steamboat Road, 3rd Floor</com:street2>
<com:city>Greenwich</com:city>
<com:stateOrCountry>CT</com:stateOrCountry>
<com:zipCode>06830</com:zipCode>
</personAddress>
</notificationInfo>
</authorizedPersons>
</coverPageHeader>
<reportingPersons>
<reportingPersonInfo>
<reportingPersonCIK>0001577524</reportingPersonCIK>
<reportingPersonName>Sarissa Capital Management LP</reportingPersonName>
<fundType>WC</fundType>
<citizenshipOrOrganization>DE</citizenshipOrOrganization>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>33470000</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>33470000</sharedDispositivePower>
<aggregateAmountOwned>33470000</aggregateAmountOwned>
<isAggregateExcludeShares>N</isAggregateExcludeShares>
<percentOfClass>8.08</percentOfClass>
<typeOfReportingPerson>PN</typeOfReportingPerson>
</reportingPersonInfo>
<reportingPersonInfo>
<reportingPersonCIK>0001361754</reportingPersonCIK>
<reportingPersonName>Alexander J Denner</reportingPersonName>
<fundType>AF</fundType>
<citizenshipOrOrganization>X1</citizenshipOrOrganization>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>33470000</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>33470000</sharedDispositivePower>
<aggregateAmountOwned>33470000</aggregateAmountOwned>
<isAggregateExcludeShares>N</isAggregateExcludeShares>
<percentOfClass>8.08</percentOfClass>
<typeOfReportingPerson>IN</typeOfReportingPerson>
</reportingPersonInfo>
</reportingPersons>
<items1To7>
<item1>
<securityTitle>Ordinary Shares, par value 50 pence per share</securityTitle>
<issuerName>Amarin Corporation PLC/UK</issuerName>
<issuerPrincipalAddress>
<com:street1>One Central Plaza, 5th Floor</com:street1>
<com:street2>36 Dame Street</com:street2>
<com:city>Dublin 2</com:city>
<com:stateOrCountry>L2</com:stateOrCountry>
<com:zipCode>D02 EF64</com:zipCode>
</issuerPrincipalAddress>
<commentText>This Amendment No. 15 to Schedule 13D ("Amendment No. 15") relates to American Depositary Shares ("ADS(s)"), each ADS presently representing one ordinary share, par value 50 pence per share (the "Ordinary Shares"), issued by Amarin Corporation plc, a company incorporated under the laws of England and Wales (the "Issuer"), and amends the initial statement on Schedule 13D filed with the Securities and Exchange Commission (the "SEC") on January 24, 2022 (the "Initial Schedule 13D"), as amended by Amendment No. 1 to Schedule 13D filed on June 3, 2022, Amendment No. 2 to Schedule 13D filed on June 16, 2022, Amendment No. 3 to Schedule 13D filed on October 11, 2022, Amendment No. 4 to Schedule 13D filed on January 11, 2023, Amendment No. 5 to Schedule 13D filed on January 19, 2023, Amendment No. 6 to Schedule 13D filed on February 8, 2023, Amendment No. 7 to Schedule 13D filed on February 10, 2023, Amendment No. 8 to Schedule 13D filed on February 14, 2023, Amendment No. 9 to Schedule 13D filed on February 15, 2023, Amendment No. 10 to Schedule 13D filed on February 21, 2023, Amendment No. 11 to Schedule 13D filed on February 27, 2023, Amendment No. 12 to Schedule 13D filed on February 28, 2023, Amendment No. 13 to Schedule 13D filed on September 5, 2023 and Amendment No. 14 to Schedule 13D filed on December 5, 2023 (the Initial Schedule 13D as so amended, the "Schedule 13D"). All capitalized terms contained herein but not otherwise defined shall have the meanings ascribed to such terms in the Schedule 13D.&#13;
&#13;
This Amendment No. 15 is being filed to amend Item 4 and Item 5(a) as follows:</commentText>
</item1>
<item4>
<transactionPurpose>On March 25, 2025, Mr. Mark DiPaolo, a member of Issuer's board of directors (the "Board"), notified the Issuer that he does not intend to stand for reelection to the Board at the Issuer's 2025 Annual Meeting of Shareholders.</transactionPurpose>
</item4>
<item5>
<percentageOfClassSecurities>The Reporting Persons may be deemed to beneficially own, in the aggregate, 33,470,000 Shares representing approximately 8.08% of the outstanding Shares. Percentages of the outstanding Shares are based upon the 414,186,296 Shares outstanding as of February 28, 2025, including 405,383,488 ADSs, and 8,802,808 Ordinary Shares, as set forth in the Form 10-K of the Issuer filed with the SEC on March 12, 2025.</percentageOfClassSecurities>
</item5>
</items1To7>
<signatureInfo>
<signaturePerson>
<signatureReportingPerson>Sarissa Capital Management LP</signatureReportingPerson>
<signatureDetails>
<signature>/s/ Mark DiPaolo</signature>
<title>Mark DiPaolo/General Counsel</title>
<date>03/25/2025</date>
</signatureDetails>
</signaturePerson>
<signaturePerson>
<signatureReportingPerson>Alexander J Denner</signatureReportingPerson>
<signatureDetails>
<signature>/s/ Alexander J Denner</signature>
<title>Alexander J Denner</title>
<date>03/25/2025</date>
</signatureDetails>
</signaturePerson>
</signatureInfo>
</formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
