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Share-Based Compensation (Tables)

6 Months Ended

Apr. 30, 2026

Share-Based Payment Arrangement [Abstract]

Schedule of Shares Reserved for Future Issuance Under the Plan

As of April 30, 2026, and October 31, 2025, the Company has reserved the following Common Shares for the exercise of Common Share warrants, share options, restricted share units, and remaining shares reserved for future issuance under the 2023 Plan and options granted outside of the 2023 Plan as part of the inducement grants:

		April 30,				October 31,
		2026				2025
Warrants to purchase common shares			8,552,818				8,511,968
Incentive options to purchase common shares awarded pursuant to the 2023 Plan			8,700,583				5,717,948
Inducement grant stock options awarded outside of the 2023 Plan			3,315,350				3,315,350
Restricted share units awarded pursuant to the 2023 Plan			266,025				—
Pre-funded warrants to purchase common shares			2,735,295				—
Remaining shares reserved for future issuance under the 2023 Plan			2,916,016				2,933,304
Remaining shares reserved for future issuance under ESSP			2,000,000				2,000,000
Total			28,486,087				22,478,570

Schedule of Assumptions Used to Determine Grant-Date Fair Value of Stock Options

The assumptions that the Company used to determine the grant-date fair value of stock options during the three and six months ended April 30, 2026 and 2025 are summarized below:

	Three months ended April 30,									Six months ended April 30,
	2026					2025				2026					2025
Expected term (in years)			—			6.08					6.03-6.08				6.02-6.08
Expected volatility			—			82.39%					82.39-82.48%				81.24-82.39%
Risk-free interest rate			—			4.01%					3.9-3.91%				4.01-4.49%
Expected dividend yield			—				—					—				—
Fair value of common shares and exercise price of options (USD)	$		—		$	4.44				$	9.53			$	4.44-7.39

Summary of Stock Option Activity

The following table summarizes the Company’s stock option activity:

		Number of Shares				Weighted- Average Exercise Price				Weighted- Average Remaining Contractual Term (in years)				Aggregate Intrinsic Value
Outstanding as of October 31, 2025			9,033,298			$	6.93				8.5			$	10,979
Granted			3,161,490				9.53
Exercised			(117,868	)			2.38
Forfeited or expired			(60,987	)			8.14
Outstanding as of April 30, 2026			12,015,933			$	7.63				8.5			$	10,865
Options vested and exercisable as of April 30, 2026			3,929,761			$	6.77				7.1			$	6,561
Options unvested as of April 30, 2026			8,086,172			$	8.04				9.1			$	4,304

Summary of Restricted Share Unit Activity

The following table summarizes the restricted share unit activity under the 2023 Plan:

		Number of Shares				Weighted- Average Grate Date Fair Value
Outstanding as of October 31, 2025			—			$	—
Granted			272,925				9.53
Vested			—				—
Forfeited or expired			(6,900	)			9.53
Outstanding as of April 30, 2026			266,025			$	9.53

Summary of Share-based Compensation Expense

Share-based compensation expense included in the Company’s consolidated statements of operations and comprehensive loss was as follows:

		Three Months Ended April 30,								Six Months Ended April 30,
		2026				2025				2026				2025
Research and development		$	1,627			$	888			$	2,631			$	1,513
General and administrative			2,518				1,762				4,317				2,946
Total share-based compensation expense		$	4,145			$	2,650			$	6,948			$	4,459

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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