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Stock-Based Awards (Tables)

9 Months Ended

Jun. 30, 2025

Summary of Stock Option Activity Including Performance Based Options

The following table summarizes stock option activity, including performance-based options, for the year-to-date period ending June 30, 2025:

		Shares Issuable Under Options				Weighted Average Exercise Price				Weighted Average Remaining Contractual Term				Aggregate Intrinsic Value
		(in thousands)								(in years)				(in thousands)
Outstanding as of September 30, 2024			5,184			$	42.67				6.3			$	1,416
Granted			1,182				8.62
Exercised			(11	)			8.99
Forfeited			(88	)			20.37
Expired			(314	)			47.98
Outstanding as of June 30, 2025			5,953			$	36.02				6.4			$	92
Options vested and expected to vest as of    June 30, 2025			5,953			$	36.02				6.4			$	92
Options exercisable as of June 30, 2025			3,873			$	46.84				5.2			$	17

Summary of Restricted Stock Unit Activity

The following table summarizes the restricted stock unit activity for the year-to-date period ending June 30, 2025:

		Restricted Stock Units				Weighted Average Grant Date Fair Value
		(in thousands)
Unvested as of September 30, 2024			428			$	36.37
Granted			176				8.67
Vested			(146	)			41.35
Cancelled			(44	)			16.71
Unvested as of June 30, 2025			414			$	24.92

Stock-Based Compensation Expense

During the three and nine months ended June 30, 2025 and 2024, the Company recognized the following stock-based compensation expense:

		Three Months Ended June 30,								Nine Months Ended June 30,
		2025				2024				2025				2024
		(in thousands)
Research and development		$	1,783			$	1,738			$	4,605			$	5,587
General and administrative			2,394				3,679				9,926				13,490
		$	4,177			$	5,417			$	14,531			$	19,077

		Three Months Ended June 30,								Nine Months Ended June 30,
		2025				2024				2025				2024
		(in thousands)
Stock options		$	2,805			$	3,632			$	9,149			$	11,805
Restricted stock units			1,262				1,525				4,011				4,597
rTSRUs			110				260				557				963
Performance stock units			—				—				814				1,712
		$	4,177			$	5,417			$	14,531			$	19,077

Performance Share Units and Relative Total Stockholder Return Units [Member]

Summary of PSUs and rTSRUs Activity

The following table summarizes PSU and rTSRU activity (at target) for the year-to-date period ending June 30, 2025:

		PSUs								rTSRUs
		Shares				Weighted Average Grant Date Fair Value				Shares				Weighted Average Grant Date Fair Value
		(in thousands)								(in thousands)
Unvested as of September 30, 2024			92			$	27.98				92			$	25.09
Granted			69				20.44				46				8.57
Vested			(68	)			47.24				—				—
Cancelled			—				—				(45	)			40.32
Unvested as of June 30, 2025			93			$	8.47				93			$	9.57

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- Definition

Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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Tabular disclosure of the changes in outstanding nonvested performance-based units.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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