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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Cash flows from operating activities    
Net loss $ (63,189) $ (87,222)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 14,531 19,077
Depreciation and amortization expense 3,302 1,857
Non-cash interest associated with the sale of future royalties (1,399) (620)
Non-cash royalty revenue (2,020) 514
Amortization of premiums on marketable securities 1,461 64
Loss on disposal of property and equipment 6 0
Change in operating assets and liabilities:    
Accounts receivable (1,687) 438
Prepaid expenses and other current assets 2,173 (1,997)
Income tax receivable 31,975 (1,451)
Operating lease, right-of-use assets 3,607 4,558
Other long-term assets 0 698
Accounts payable (588) 1,124
Accrued expenses (2,360) (6,047)
Operating lease liabilities 1,384 1,079
Other long-term liabilities 21 (436)
Net cash used in operating activities (12,783) (68,364)
Cash flows from investing activities    
Purchase of marketable securities (141,008) (307,283)
Proceeds from maturities and sale of marketable securities 190,497 355,442
Purchase of property and equipment (11,438) (8,997)
Net cash provided by investing activities 38,051 39,162
Cash flows from financing activities    
Payments on royalty sale liability, net of imputed interest (18,124) (20,215)
Payments for settlement of share-based awards (267) (275)
Proceeds from the exercise of stock options 94 79
Net cash used in financing activities (18,297) (20,411)
Net increase (decrease) in cash, cash equivalents and restricted cash 6,971 (49,613)
Cash, cash equivalents and restricted cash at beginning of period 41,201 89,356
Cash, cash equivalents and restricted cash at end of period 48,172 39,743
Supplemental disclosure of non-cash information:    
Purchases of fixed assets included in accounts payable and accrued expenses 1,396 6,416
Operating lease liabilities arising from obtaining right-of-use assets 1,199 22,975
Supplemental disclosure of cash flow information    
Cash paid for interest 7,185 9,187
Cash received from tenant improvement allowances 5,146 4,622
Cash received from income tax refund $ 33,785 $ 0