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  <xsd:element abstract="true" id="quad_RevolvingCreditFacilityAndTermLoanAMember" name="RevolvingCreditFacilityAndTermLoanAMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_RiseInteractiveMember" name="RiseInteractiveMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
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  <xsd:element id="quad_ScheduleofFairValueMeasurementsinCollectiveTrustsTableTextBlock" name="ScheduleofFairValueMeasurementsinCollectiveTrustsTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
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  <xsd:element id="quad_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsSettledInPeriodWeightedAverageGrantDateFairValue" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsSettledInPeriodWeightedAverageGrantDateFairValue" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="duration" />
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  <xsd:element id="quad_SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentsOtherthanOptionsOutstandingWeightedAverageGrantDateFairValue" name="SharebasedCompensationArrangementbySharebasedPaymentAwardEquityInstrumentsOtherthanOptionsOutstandingWeightedAverageGrantDateFairValue" nillable="true" substitutionGroup="xbrli:item" type="num:perShareItemType" xbrli:periodType="instant" />
  <xsd:element id="quad_SharebasedCompensationArrangementbySharebasedPaymentAwardFloorExercisePriceasaPercentageofGrantDatePrice" name="SharebasedCompensationArrangementbySharebasedPaymentAwardFloorExercisePriceasaPercentageofGrantDatePrice" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
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  <xsd:element id="quad_TaxCreditCarryforwardAmountNotSubjectToExpiration" name="TaxCreditCarryforwardAmountNotSubjectToExpiration" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="quad_TaxCutsAndJobsActOf2017IncompleteAccountingChangeInTaxRateUncertainTaxPositions" name="TaxCutsAndJobsActOf2017IncompleteAccountingChangeInTaxRateUncertainTaxPositions" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="quad_TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateDeferredTaxLiabilityProvisionalIncomeTaxBenefit" name="TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateDeferredTaxLiabilityProvisionalIncomeTaxBenefit" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="quad_TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateProvisionalIncomeTaxExpenseBenefit" name="TaxCutsandJobsActof2017IncompleteAccountingChangeinTaxRateProvisionalIncomeTaxExpenseBenefit" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="quad_Taxrelatedliabilities" name="Taxrelatedliabilities" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="quad_TermLoanBMember" name="TermLoanBMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_TermLoanMember" name="TermLoanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_TerminationForDeathMember" name="TerminationForDeathMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_TerminationForRetirementOrDisabilityMember" name="TerminationForRetirementOrDisabilityMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_ThirdAmendmentToSeniorSecuredCreditFacilityMember" name="ThirdAmendmentToSeniorSecuredCreditFacilityMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_TotalProductsMember" name="TotalProductsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_TotalServicesMember" name="TotalServicesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_TrademarksPatentsAndLicensingAgreementsMember" name="TrademarksPatentsAndLicensingAgreementsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_TransactionRelatedChargesMember" name="TransactionRelatedChargesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_UnitedStatesPrintandRelatedServicesMember" name="UnitedStatesPrintandRelatedServicesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="quad_UnrestrictedsubsidiariesundertheSeniorUnsecuredNotesindentureasapercentageoftotalconsolidatednetsales" name="UnrestrictedsubsidiariesundertheSeniorUnsecuredNotesindentureasapercentageoftotalconsolidatednetsales" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="quad_UnrestrictedsubsidiariesundertheSeniorUnsecuredNotesindentureaspercentageoftotalconsolidatedassets" name="UnrestrictedsubsidiariesundertheSeniorUnsecuredNotesindentureaspercentageoftotalconsolidatedassets" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="quad_WeightedAverageNumberOfCommonSharesOutstandingAbstract" name="WeightedAverageNumberOfCommonSharesOutstandingAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_YearofExpirationAxis" name="YearofExpirationAxis" nillable="true" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="quad_YearofExpirationDomain" name="YearofExpirationDomain" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
</xsd:schema>
